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Institut für Physiologie und Pathophysiologie

Publikationen 2007 - 2009

2009

42.

Limbourg A, Korff T, Napp LC, Schaper W, Drexler H, Limbourg FP. Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia. Nat Protoc. 2009;4(12):1737-46. Epub 2009 Nov 5.

41.

Wagner AH, Kautz O, Fricke K, Zerr-Fouineau M, Demicheva E, Güldenzoph B, Bermejo JL, Korff T, Hecker M. Upregulation of glutathione peroxidase offsets stretch-induced proatherogenic gene expression in human endothelial cells. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1894-901. Epub 2009 Sep 3.

40.

Asif AR, Hecker M, Cattaruzza M. Disinhibition of SOD-2 expression to compensate for a genetically determined NO deficit in endothelial cells--brief report. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1890-3. Epub 2009 Aug 20.

39.

Stojanovic T, Wagner AH, Wang S, Kiss E, Rockstroh N, Bedke J, Gröne HJ, Hecker M. STAT-1 decoy oligodeoxynucleotide inhibition of acute rejection in mouse heart transplants. Basic Res Cardiol. 2009 Nov;104(6):719-29. Epub 2009 Apr 8.

38.

Laib AM, Bartol A, Alajati A, Korff T, Weber H, Augustin HG. Spheroid-based human endothelial cell microvessel formation in vivo. Nat Protoc. 2009;4(8):1202-15. Epub 2009 Jul 30.

37.

Asif AR, Oellerich M, Armstrong VW, Hecker M, Cattaruzza M. T-786C polymorphism of the NOS-3 gene and the endothelial cell response to fluid shear stress-a proteome analysis. J Proteome Res. 2009 Jun;8(6):3161-8.

36.

Zerr-Fouineau M, Jourdain M, Boesch C, Hecker M, Bronner C, Schini-Kerth VB. Certain progestins prevent the enhancing effect of 17beta-estradiol on NO-mediated inhibition of platelet aggregation by endothelial cells. Arterioscler Thromb Vasc Biol. 2009 Apr;29(4):586-93. Epub 2008 Dec 18.

2008

35.

Plaschke K, Staub J, Ernst E, Marti HH. VEGF overexpression improves mice cognitive abilities after unilateral common carotid artery occlusion. Exp Neurol. 2008 Dec;214(2):285-92. Epub 2008 Sep 11.

34.

Pfaff D, Héroult M, Riedel M, Reiss Y, Kirmse R, Ludwig T, Korff T, Hecker M, Augustin HG. Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes. J Cell Sci. 2008 Nov 15;121(Pt 22):3842-50. Epub 2008 Oct 28.

33.

Graier WF, Hecker M. Endothelial H2O2: a bad guy turning good?  Arterioscler Thromb Vasc Biol. 2008 Oct;28(10):1691-3. No abstract available.

32.

Wirz W, Antoine M, Tag CG, Gressner AM, Korff T, Hellerbrand C, Kiefer P. Hepatic stellate cells display a functional vascular smooth muscle cell phenotype in a three-dimensional co-culture model with endothelial cells. Differentiation. 2008 Sep;76(7):784-94. Epub 2008 Jan 3.

31.

Stadlbauer TH, Wagner AH, Hölschermann H, Fiedel S, Fingerhuth H, Tillmanns H, Bohle RM, Hecker M. AP-1 and STAT-1 decoy oligodeoxynucleotides attenuate transplant vasculopathy in rat cardiac allografts. Cardiovasc Res. 2008 Sep 1;79(4):698-705. Epub 2008 May 29.

30.

Demicheva E, Hecker M, Korff T. Stretch-induced activation of the transcription factor activator protein-1 controls monocyte chemoattractant protein-1 expression during arteriogenesis. Circ Res. 2008 Aug 29;103(5):477-84. Epub 2008 Jul 31.

29.

Morawietz H, Wagner AH, Hecker M, Goettsch W. Endothelin receptor B-mediated induction of c-jun and AP-1 in response to shear stress in human endothelial cells. Can J Physiol Pharmacol. 2008 Aug;86(8):499-504.

28.

Korff T, Braun J, Pfaff D, Augustin HG, Hecker M. Role of ephrinB2 expression in endothelial cells during arteriogenesis: impact on smooth muscle cell migration and monocyte recruitment. Blood. 2008 Jul 1;112(1):73-81. Epub 2008 Apr 29.

27.

Webler AC, Popp R, Korff T, Michaelis UR, Urbich C, Busse R, Fleming I. Cytochrome P450 2C9-induced angiogenesis is dependent on EphB4. Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1123-9. Epub 2008 Mar 13.

26.

Alajati A, Laib AM, Weber H, Boos AM, Bartol A, Ikenberg K, Korff T, Zentgraf H, Obodozie C, Graeser R, Christian S, Finkenzeller G, Stark GB, Héroult M, Augustin HG. Spheroid-based engineering of a human vasculature in mice. Nat Methods. 2008 May;5(5):439-45. Epub 2008 Apr 6.

25.

Hecker M, Wagner S, Henning SW, Wagner AH. Decoy oligodeoxynucleotides to treat inflammatory diseases. (book chapter) In: Therapeutic Oligonucleotides 2008; (ed. Kurreck J) RSC Publishing, Cambridge, U.K., pp. 163-188.

24.

Goettsch W, Gryczka C, Korff T, Ernst E, Goettsch C, Seebach J, Schnittler HJ, Augustin HG, Morawietz H. Flow-dependent regulation of angiopoietin-2. J Cell Physiol. 2008 Feb;214(2):491-503.

23.

Cattaruzza M, Hecker M. Protein carbonylation and decarboylation: a new twist to the complex response of vascular cells to oxidative stress. Circ Res. 2008 Feb 15;102(3):273-4.

22.

Wagner AH, Wittjen I, Stojanovic T, Middel P, Meingassner JG, Hecker M. Signal transducer and activator of transcription 1 decoy oligodeoxynucleotide suppression of contact hypersensitivity. J Allergy Clin Immunol. 2008 Jan;121(1):158-165.e5. Epub 2007 Nov 5.

2007

21.

Korff T, Aufgebauer K, Hecker M. Cyclic stretch controls the expression of CD40 in endothelial cells by changing their transforming growth factor-beta1 response. Circulation. 2007 Nov 13;116(20):2288-97. Epub 2007 Oct 29.

20.

Stojakovic M, Krzesz R, Wagner AH, Hecker M. CD154-stimulated GM-CSF release by vascular smooth muscle cells elicits monocyte activation--role in atherogenesis. J Mol Med. 2007 Nov;85(11):1229-38. Epub 2007 Jul 10.

19.

Melchers I, Cattaruzza M. Gendefekt im Promoter der endothelialen NO-Synthase als Risikofaktor für Rheumatoide Arthritis. [A gene defect in the promoter of the endothelial NO synthase as a risk factor for rheumatoid arthritis.] Z Rheumatol. 2007 Jul;66(4):326-7. Review.

18.

Stojanovic T, Scheele L, Wagner AH, Middel P, Bedke J, Lautenschläger I, Leister I, Panzner S, Hecker M. STAT-1 decoy oligonucleotide improves microcirculation and reduces acute rejection in allogeneic rat small bowel transplants. Gene Ther. 2007 Jun;14(11):883-90. Epub 2007 Mar 15.


Neue Publikationen

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Inhibition of cardiac Kv4.3 (Ito) channel isoforms by class I antiarrhythmic drugs lidocaine and mexiletine. Eur J Pharmacol. 2020 Aug 5;880:173159. doi: 10.1016/j.ejphar.2020.173159. Epub 2020 Apr 29.

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Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nat Rev Drug Discov. 2020 Jul 24. doi: 10.1038/s41573-020-0072-x. Online ahead of print.

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Lactate Attenuates Synaptic Transmission and Affects Brain Rhythms Featuring High Energy Expenditure. iScience. 2020 Jul 24;23(7):101316. doi: 10.1016/j.isci.2020.101316. Epub 2020 Jun 27.

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A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice. Int J Mol Sci. 2020 Jul 10;21(14):4887. doi:10.3390/ijms21144887.

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Neuronal gamma oscillations and activity-dependent potassium transients remain regular after depletion of microglia in postnatal cortex tissue. J Neurosci Res. 2020 Jul 7. doi: 10.1002/jnr.24689. Online ahead of print.

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Marfan-Syndrom: Eine therapeutische Herausforderung für die Langzeitbehandlung (3/3). Medinlux. 2020 Jun;6:16-20. Review.

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Amyloid, APP, and Electrical Activity of the Brain. Neuroscientist. 2020 Jun;26(3):231-251. doi: 10.1177/1073858419882619. Epub 2019 Nov 29.

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Selective inhibition of mitochondrial respiratory complexes controls the transition of microglia into a neurotoxic phenotype in situ. Brain Behav Immun. 2020 May 21. pii: S0889-1591(20)30209-9. doi: 10.1016/j.bbi.2020.05.052. [Epub ahead of print]

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Synchronicity of excitatory inputs drives hippocampal networks to distinct oscillatory patterns. Hippocampus. 2020 May 15. doi: 10.1002/hipo.23214. [Epub ahead of print]

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Vascular Signaling in Allogenic Solid Organ Transplantation - The Role of Endothelial Cells. Front Physiol. 2020 May 8;11:443. doi: 10.3389/fphys.2020.00443. eCollection 2020. Review.

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Plant "intelligence" changes nothing. EMBO Rep. 2020 May 6;21(5):e50395. doi: 10.15252/embr.202050395. Epub 2020 Apr 16.

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Marfan-Syndrom: Eine therapeutische Herausforderung für die Langzeitbehandlung (2/3). Medinlux. 2020 May;5:16-23. Review.

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Functional association of a CD40 gene single nucleotide polymorphism with the pathogenesis of coronary heart disease. Cardiovasc Res. 2020 May 1;116(6):1214-1225. doi: 10.1093/cvr/cvz206. Epub 2019 Aug 2.

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Risk and protective factors for post-thrombotic syndrome after deep venous thrombosis. J Vasc Surg Venous Lymphat Disord. 2020 May;8(3):390-395. doi: 10.1016/j.jvsv.2019.10.012. Epub 2019 Dec 14.

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Mild metabolic stress is sufficient to disturb the formation of pyramidal cell ensembles during gamma oscillations. J Cereb Blood Flow Metab. 2019 Dec 16:271678X19892657. doi: 10.1177/0271678X19892657. [Epub ahead of print

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The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms. J Cereb Blood Flow Metab. 2019 Nov 13:271678X19887777. doi: 10.1177/0271678X19887777. [Epub ahead of print]


Institut für
Physiologie und Pathophysiologie

Universität Heidelberg

Im Neuenheimer Feld 326

69120 Heidelberg

Telefon:+49 6221 54-4056
Telefax:+49 6221 54-6364
E-Mail:susanne.bechtel@
physiologie.uni-heidelberg.de