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Institut für Physiologie und Pathophysiologie

Publikationen 2012 - 2015

2015

39.

Lelli A, Nolan KA, Santambrogio S, Gonçalves AF, Schönenberger MJ, Guinot A, Frew IJ, Marti HH, Hoogewijs D, Wenger RH. Induction of long noncoding RNA MALAT1 in hypoxic mice. Hypoxia (Auckl). 2015 Oct 8;2015(3):45-52. doi: 10.2147/HP.S90555.

38.

Wenger RH, Kurtcuoglu V, Scholz CC, Marti HH, Hoogewijs D. Frequently asked questions in hypoxia research. Hypoxia (Auckl). 2015 Sep 15;2015(3):35-43. doi: 10.2147/HP.S92198.

37.

Kunze R, Urrutia A, Hoffmann A, Liu H, Helluy X, Pham M, Reischl S, Korff T, Marti HH. Dimethyl fumarate attenuates cerebral edema formation by protecting the blood-brain barrier integrity. Exp Neurol. 2015 Apr;266:99-111. doi: 10.1016/j.expneurol.2015.02.022. Epub 2015 Feb 25.

2014

36.

Lee H, Lee JK, Park MH, Hong YR, Marti HH, Kim H, Okada Y, Otsu M, Seo EJ, Park JH, Bae JH, Okino N, He X, Schuchman EH, Bae JS, Jin HK. Pathological roles of the VEGF/SphK pathway in Niemann-Pick type C neurons. Nat Commun. 2014 Nov 24;5:5514. doi: 10.1038/ncomms6514.

35.

Reischl S, Li L, Walkinshaw G, Flippin LA, Marti HH, Kunze R.  Inhibition of HIF prolyl-4-hydroxylases by FG-4497 Reduces Brain Tissue Injury and Edema Formation during Ischemic Stroke. PLoS One. 2014 Jan 7;9(1):e84767. doi: 10.1371/journal.pone.0084767.

2013

34.

Corcoran A, Kunze R, Harney SC, Breier G, Marti HH, O'Connor JJ. A role for prolyl hydroxylase domain proteins in hippocampal synaptic plasticity. Hippocampus. 2013 Oct;23(10):861-72. doi: 10.1002/hipo.22142. Epub 2013 May 15.

33.

Religa P, Cao R, Religa D, Xue Y, Bogdanovic N, Westaway D, Marti HH, Winblad B, Cao Y. VEGF significantly restores impaired memory behavior in Alzheimer's mice by improvement of vascular survival. Sci Rep. 2013 Jun 24;3:2053. doi: 10.1038/srep02053.

32.

Kaufmann MR, Barth S, Konietzko U, Wu B, Egger S, Kunze R, Marti HH, Hick M, Müller U, Camenisch G, Wenger RH. Dysregulation of Hypoxia-Inducible Factor by Presenilin/γ-Secretase Loss-of-Function Mutations. J Neurosci. 2013 Jan 30;33(5):1915-26. doi: 10.1523/JNEUROSCI.3402-12.2013.

2012

31.

Kunze R, Zhou W, Veltkamp R, Wielockx B, Breier G, Marti HH. Neuron-Specific Prolyl-4-Hydroxylase Domain 2 Knockout Reduces Brain Injury After Transient Cerebral Ischemia. Stroke. 2012 Oct;43(10):2748-56. Epub 2012 Aug 28.


Neue Publikationen

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The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms. J Cereb Blood Flow Metab. 2019 Nov 13:271678X19887777. doi: 10.1177/0271678X19887777. [Epub ahead of print]

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Shaping the heart: Structural and functional maturation of iPSC-cardiomyocytes in 3D-micro-scaffolds. Biomaterials. 2020 Jan;227:119551. doi: 10.1016/j.biomaterials.2019.119551. Epub 2019 Oct 19.

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Simulation Strategies for Calcium Microdomains and Calcium Noise. Adv Exp Med Biol. 2020;1131:771-797. doi: 10.1007/978-3-030-12457-1_31.

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Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer. Int J Cancer. 2019 Dec 15;145(12):3299-3310. doi: 10.1002/ijc.32481. Epub 2019 Jun 19.

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Persistent increase in ventral hippocampal long-term potentiation by juvenile stress: A role for astrocytic glutamine synthetase. Glia. 2019 Dec;67(12):2279-2293. doi: 10.1002/glia.23683. Epub 2019 Jul 17.

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4.2 Kreislauf. In: Physiologie hoch2 (Gründer S, Schlüter KD, eds.) Urban & Fischer Verlag/Elsevier GmbH 2019, pp. 192-225. ISBN 978-3-437-43461-7

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The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain. FASEB J. 2019 Nov;33(11):12812-12824. doi: 10.1096/fj.201901385RR. Epub 2019 Aug 30.

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TRPC channels are not required for graded persistent activity in entorhinal cortex neurons. Hippocampus. 2019 Nov;29(11):1038-1048. doi: 10.1002/hipo.23094. Epub 2019 Apr 19.

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The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease. Biochem Biophys Res Commun. 2019 Oct 29;519(1):141-147. doi: 10.1016/j.bbrc.2019.08.150. Epub 2019 Aug 31.

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Endothelial cell modulation of cardiomyocyte gene expression. Exp Cell Res. 2019 Oct 15;383(2):111565. doi: 10.1016/j.yexcr.2019.111565. Epub 2019 Aug 20.

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Pacemaker cell characteristics of differentiated and HCN4-transduced human mesenchymal stem cells. Life Sci. 2019 Sep 1;232:116620. doi: 10.1016/j.lfs.2019.116620. Epub 2019 Jul 7.

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Reduction of Transplant Vasculopathy by Intraoperative Nucleic Acid-based Therapy in a Mouse Aortic Allograft Model. Thorac Cardiovasc Surg. 2019 Sep;67(6):503-512. doi: 10.1055/s-0038-1673633. Epub 2018 Oct 23.

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Functional association of a CD40 gene single nucleotide polymorphism with the pathogenesis of coronary heart disease. Cardiovasc Res. 2019 Aug 2. pii: cvz206. doi: 10.1093/cvr/cvz206. [Epub ahead of print]


Institut für
Physiologie und Pathophysiologie

Universität Heidelberg

Im Neuenheimer Feld 326

69120 Heidelberg

Telefon:+49 6221 54-4035
Telefax:+49 6221 54-4038
E-Mail:sekretariat.hecker@
physiologie.uni-heidelberg.de