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Institute of Physiology and Pathophysiology

Cardiovascular Physiology

Director

 

Prof. Dr. Markus Hecker

 

Phone:

+49 6221 54-4036/4035

Fax:

+49 6221 54-4038

E-Mail:

hecker@physiologie.uni-heidelberg.de

 

Secretary

 

Barbara Richards

 

Phone:

+49 6221 54-4035

Fax:

+49 6221 54-4038

E-Mail:

sekretariat.hecker@physiologie.uni-heidelberg.de

Our Field of Research

Our research focuses on the molecular mechanisms underlying pathophysiological and physiological remodelling processes in the cardiovascular system, to define new therapeutic aproaches for cardiovascular disease.

 

At present five working groups and one project team concentrate on various research areas within this field.

 

Scientists of the division are also integrated in a number of local and national research centers and networks:

   


Recent Publications

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A reliable model for gamma oscillations in hippocampal tissue. J Neurosci Res. 2015 Jul;93(7):1067-78. doi: 10.1002/jnr.23590. Epub 2015 Mar 24.

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von Willebrand factor fibers promote cancer-associated platelet aggregation in malignant melanoma of mice and humans. Blood. 2015 May 14;125(20):3153-63. doi: 10.1182/blood-2014-08-595686. Epub 2015 Feb 24.

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Functional Characterization and Comparison of Intercellular Communication in Stem Cell-Derived Cardiomyocytes. Stem Cells. 2015 Apr 9. doi: 10.1002/stem.2009. [Epub ahead of print]

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Mechanism and functional impact of CD40 ligand-induced von Willebrand factor release from endothelial cells. Thromb Haemost. 2015 Apr 29;113(5):1095-108. doi: 10.1160/TH14-04-0336. Epub 2015 Jan 22.

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JAK1/STAT3 activation directly inhibits IL-12 production in dendritic cells by preventing CDK9/P-TEFb recruitment to the p35 promoter. Biochem Pharmacol. 2015 Apr 27. pii: S0006-2952(15)00242-7. doi: 10.1016/j.bcp.2015.04.019. [Epub ahead of print]

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Neuronal Network Oscillations in Neurodegenerative Diseases. Neuromolecular Med. 2015 Apr 29. [Epub ahead of print]

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Physiology-based kinetic modeling of neuronal energy metabolism unravels the molecular basis of NAD(P)H fluorescence transients. J Cereb Blood Flow Metab. 2015 Apr 22. doi: 10.1038/jcbfm.2015.70. [Epub ahead of print]

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Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro. FASEB J. 2015 Apr 9. pii: fj.14-267633. [Epub ahead of print]

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Could tuning of the inhibitory tone involve graded changes in neuronal chloride transport? Neuropharmacology. 2015 Apr 3. pii: S0028-3908(15)00118-5. doi: 10.1016/j.neuropharm.2015.03.026. [Epub ahead of print]

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Dimethyl fumarate attenuates cerebral edema formation by protecting the blood-brain barrier integrity. Exp Neurol. 2015 Apr;266:99-111. doi: 10.1016/j.expneurol.2015.02.022. Epub 2015 Feb 25.

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Development and Characterization of a Scaffold-Free 3D Spheroid Model of Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes.Tissue Eng Part C Methods. 2015 Mar 16. [Epub ahead of print]

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Widespread activation of microglial cells in the hippocampus of chronic epileptic rats correlates only partially with neurodegeneration. Brain Struct Funct. 2014 May 31. [Epub ahead of print]


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4035
Fax:+49 6221 54-4038
E-mail:sekretariat.hecker@
physiologie.uni-heidelberg.de