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Institute of Physiology and Pathophysiology

Cardiovascular Physiology

Director

 

Prof. Dr. Markus Hecker

 

Phone:

+49 6221 54-4036/4035

Fax:

+49 6221 54-4038

E-Mail:

hecker@physiologie.uni-heidelberg.de

 

Secretary

 

Barbara Richards

 

Phone:

+49 6221 54-4035

Fax:

+49 6221 54-4038

E-Mail:

sekretariat.hecker@physiologie.uni-heidelberg.de

Our Field of Research

Our research focuses on the molecular mechanisms underlying pathophysiological and physiological remodelling processes in the cardiovascular system, to define new therapeutic aproaches for cardiovascular disease.

 

At present five working groups and one project team concentrate on various research areas within this field.

 

Scientists of the division are also integrated in a number of local and national research centers and networks:

   


Update

 (further informationen)

14.07.2014

 

Dr. Larissa Pfisterer awarded the Friedrich Reutner-Prize by the Medical Faculty 

 

Recent Publications

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Advances in endothelial shear stress proteomics. Expert Rev Proteomics. 2014 Oct;11(5):611-9. doi: 10.1586/14789450.2014.933673. Epub 2014 Jul 12.

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The Symptom Complex of Familial Sinus Node Dysfunction and Myocardial Noncompaction Is Associated With Mutations in the HCN4 Channel. J Am Coll Cardiol. 2014 Aug 26;64(8):757-67. doi: 10.1016/j.jacc.2014.06.1155.

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Targeting the Ubiquitin-Proteasome System in Heart Disease: The Basis for New Therapeutic Strategies. Antioxid Redox Signal. 2014 Aug 18. [Epub ahead of print]

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MiR-134-dependent regulation of Pumilio-2 is necessary for homeostatic synaptic depression. EMBO J. 2014 Aug 5. pii: e201487921. [Epub ahead of print]

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Highly energized inhibitory interneurons are a central element for information processing in cortical networks. J Cereb Blood Flow Metab. 2014 Aug;34(8):1270-82. doi: 10.1038/jcbfm.2014.104. Epub 2014 Jun 4.

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Bortezomib protects from varicose-like venous remodeling. FASEB J. 2014 Aug;28(8):3518-27. doi: 10.1096/fj.14-250464. Epub 2014 Apr 25.

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Ion-dynamics in hepatitis C virus p7 helical transmembrane domains - a molecular dynamics simulation study. Biophys Chem. 2014 Aug;192C:33-40. doi: 10.1016/j.bpc.2014.06.001. Epub 2014 Jun 16.

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EphrinB-mediated reverse signalling controls junctional integrity and pro-inflammatory differentiation of endothelial cells. Thromb Haemost. 2014 Jul 3;112(1):151-63. doi: 10.1160/TH13-12-1034. Epub 2014 Feb 13.

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RGS5 promotes arterial growth during arteriogenesis. EMBO Mol Med. 2014 Jun 27;6(8):1075-89. doi: 10.15252/emmm.201403864.

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Widespread activation of microglial cells in the hippocampus of chronic epileptic rats correlates only partially with neurodegeneration. Brain Struct Funct. 2014 May 31. [Epub ahead of print]

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The left and right ventricle in the grip of protein degradation: Similarities and unique patterns in regulation. J Mol Cell Cardiol. 2014 Jul;72:52-5. doi: 10.1016/j.yjmcc.2014.02.016. Epub 2014 Mar 10.

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Optimized temporally deconvolved Ca2+ imaging allows identification of spatiotemporal activity patterns of CA1 hippocampal ensembles. Neuroimage. 2014 Jul;94:239-49. doi: 10.1016/j.neuroimage.2014.03.030. Epub 2014 Mar 17.


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4035
Fax:+49 6221 54-4038
E-Mail:physiologie@uni-hd.de