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Institute of Physiology and Pathophysiology

Cardiovascular Physiology

Director

 

Prof. Dr. Markus Hecker

 

Phone:

+49 6221 54-4036/4035

Fax:

+49 6221 54-4038

E-Mail:

hecker@physiologie.uni-heidelberg.de

 

Secretary

 

Barbara Richards

 

Phone:

+49 6221 54-4035

Fax:

+49 6221 54-4038

E-Mail:

sekretariat.hecker@physiologie.uni-heidelberg.de

Our Field of Research

Our research focuses on the molecular mechanisms underlying pathophysiological and physiological remodelling processes in the cardiovascular system, to define new therapeutic aproaches for cardiovascular disease.

 

At present four working groups and one project team concentrate on various research areas within this field.

 

Scientists of the division are also integrated in a number of local and national research centers and networks:

   


28.5.2013       14:00   /   INF 306, Seminar Room 13

 

Coronary aspirate - a signature of coronary atherosclerosis

PD Dr. Petra Kleinbongard

Institute of Pathophysiology, Essen University Hospital, Germany 

  

Recent Publications

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The tetraspanin network modulates MT1-MMP cell surface trafficking. Int J Biochem Cell Biol. 2013 Jun;45(6):1133-44. doi: 10.1016/j.biocel.2013.02.020. Epub 2013 Mar 14.

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A role for prolyl hydroxylase domain proteins in hippocampal synaptic plasticity. Hippocampus. 2013 May 15. doi: 10.1002/hipo.22142. [Epub ahead of print]

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Effects of the GABA-uptake blocker NNC-711 on spontaneous sharp wave-ripple complexes in mouse hippocampal slices. Hippocampus. 2013 May;23(5):323-9. doi: 10.1002/hipo.22104. Epub 2013 Mar 5.

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Hippocampal Network Oscillations in APP/APLP2-Deficient Mice. PLoS One. 2013 Apr 9;8(4):e61198. doi: 10.1371/journal.pone.0061198. Print 2013.

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Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis. PLoS Biol. 2013 Mar;11(3):e1001506. doi: 10.1371/journal.pbio.1001506. Epub 2013 Mar 12.

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Establishment of a Secondary Screening Assay for P/Q-type Calcium Channel Blockers. Comb Chem High Throughput Screen. 2013 Mar 1;16(3):233-43.

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Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: Prevention of Aβ-induced synaptic deficits by calcium channel blockers. Eur J Pharmacol. 2013 Feb 28;702(1-3):44-55. doi: 10.1016/j.ejphar.2013.01.030. Epub 2013 Jan 30.

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From chaos to split-ups--SHG microscopy reveals a specific remodelling mechanism in ageing dystrophic muscle. J Pathol. 2013 Feb;229(3):477-85. doi: 10.1002/path.4136.

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Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization. Exp Neurol. 2013 Jan 16. doi:pii: S0014-4886(13)00018-6. 10.1016/j.expneurol.2013.01.005. [Epub ahead of print]

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Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation. Eur Heart J. 2012 Nov 23. [Epub ahead of print]

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Development of coherent neuronal activity patterns in mammalian cortical networks: common principles and local hetereogeneity. Mech Dev. 2012 Sep 29. pii: S0925-4773(12)00091-3. doi: 10.1016/j.mod.2012.09.006. [Epub ahead of print]


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4056
Fax:+49 6221 54-4038
E-Mail:physiologie@uni-hd.de