Korff Group
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Endothelial Spheroids: An Advanced Replacement Model (3Rs principle)
for the Study of Endothelial Differentiation and Angiogenesis
Welcome to our web page specifically dedicated to an endothelial spheroid-based in vitro cell culture system developed in our group. Here we provide some general background on this technique as well as more detailed, up-to-date information for researchers already using this experimental approach in their groups.
Recent Publications
* | Pacemaker cell characteristics of differentiated and HCN4-transduced human mesenchymal stem cells. Life Sci. 2019 Jul 7:116620. doi: 10.1016/j.lfs.2019.116620. [Epub ahead of print] |
* | Plants Neither Possess nor Require Consciousness. Trends Plant Sci. 2019 Jun 21. pii: S1360-1385(19)30126-8. doi: 10.1016/j.tplants.2019.05.008. [Epub ahead of print] Review. |
* | 15-Deoxy-Δ12,14-Prostaglandin J2 Reinforces the Anti-Inflammatory Capacity of Endothelial Cells with a Genetically Determined Nitric Oxide Deficit. Circ Res. 2019 Jun 19. doi: 10.1161/CIRCRESAHA.118.313820. [Epub ahead of print] |
* | Angioneurins-key regulators of blood-brain barrier integrity during hypoxic and ischemic brain injury. Prog Neurobiol. 2019 Jul;178:101611. doi: 10.1016/j.pneurobio.2019.03.004. Epub 2019 Apr 7. Review. |
* | Marfan syndrome: A therapeutic challenge for long-term care. Biochem Pharmacol. 2019 Jun;164:53-63. doi: 10.1016/j.bcp.2019.03.034. Epub 2019 Mar 27. |
* | Characterization of the Subventricular-Thalamo-Cortical Circuit in the NP-C Mouse Brain, and New Insights Regarding Treatment. Mol Ther. 2019 May 16. pii: S1525-0016(19)30222-9. doi: 10.1016/j.ymthe.2019.05.008. [Epub ahead of print] |
* | TRPC channels are not required for graded persistent activity in entorhinal cortex neurons. Hippocampus. 2019 Apr 19. doi: 10.1002/hipo.23094. [Epub ahead of print] |
* | Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ. Proc Natl Acad Sci U S A. 2019 Feb 19. pii: 201813562. doi: 10.1073/pnas.1813562116. [Epub ahead of print] |
* | Reduction of Transplant Vasculopathy by Intraoperative Nucleic Acid-based Therapy in a Mouse Aortic Allograft Model. Thorac Cardiovasc Surg. 2018 Oct 23. doi: 10.1055/s-0038-1673633. [Epub ahead of print] |
Institute of Heidelberg University Im Neuenheimer Feld 326 69120 Heidelberg Germany
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