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Institute of Physiology and Pathophysiology

Neuro- and Sensory Physiology



Susanne Bechtel



+49 6221 54-4056


Our Field of Research



We are interested in synaptic inhibition and in the mechanisms underlying coordinated spatio-temporal patterns of activity within neuronal networks. Besides normal physiology, we try to contribute to the analysis of pathological conditions like epilepsy, depression and Alzheimer´s disease. We use a broad spectrum of methods, mostly electrophysiological techniques and imaging in vitro and in vivo.


Scientists of the division are also integrated in a number of regional and national research centers and networks:   


Further interesting links:





Recent Publications


Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down-regulated proportionally to neuronal loss in the human epileptic hippocampus. Glia. 2018 May;66(5):920-933. doi: 10.1002/glia.23292. Epub 2018 Jan 19.


Expansion of functional personalized cells with specific transgene combinations. Nat Commun. 2018 Mar 8;9(1):994. doi: 10.1038/s41467-018-03408-4.


Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells. Redox Biol. 2018 Feb 27;16:113-122. doi: 10.1016/j.redox.2018.02.018. [Epub ahead of print]


Respiration-Entrained Brain Rhythms Are Global but Often Overlooked. Trends Neurosci. 2018 Feb 8. pii: S0166-2236(18)30031-6. doi: 10.1016/j.tins.2018.01.007. [Epub ahead of print] Review.


Modulation of glutathione peroxidase activity by age-dependent carbonylation in glomeruli of diabetic mice. J Diabetes Complications. 2018 Feb;32(2):130-138. doi: 10.1016/j.jdiacomp.2017.11.007. Epub 2017 Nov 22.


Bringing European physiologists together. Acta Physiol (Oxf). 2018 Jan 29. doi: 10.1111/apha.13043. [Epub ahead of print]


Role of protein carbonylation in diabetes. J Inherit Metab Dis. 2018 Jan;41(1):29-38. doi: 10.1007/s10545-017-0104-9. Epub 2017 Nov 6.


Sensitive mass spectrometric assay for determination of 15-deoxy-Δ12,14-prostaglandin J2 and its application in human plasma samples of patients with diabetes. Anal Bioanal Chem. 2018 Jan;410(2):521-528. doi: 10.1007/s00216-017-0748-1. Epub 2017 Nov 16.


Magnolol inhibits venous remodeling in mice. Sci Rep. 2017 Dec 19;7(1):17820. doi: 10.1038/s41598-017-17910-0.


Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5. FASEB J. 2017 Dec 5. pii: fj.201700384RR. doi: 10.1096/fj.201700384RR. [Epub ahead of print]


AP-1 Oligodeoxynucleotides Reduce Aortic Elastolysis in a Murine Model of Marfan Syndrome. Mol Ther Nucleic Acids. 2017 Dec 15;9:69-79. doi: 10.1016/j.omtn.2017.08.014. Epub 2017 Sep 20.

Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg


Phone:+49 6221 54-4035
Fax:+49 6221 54-4038