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Institute of Physiology and Pathophysiology

Publications

 

For older publications please refer to the menu in the right-hand column.

 

Marked titles are linked to their respective abstract on a freely accessible external website.

2018

50.

Hoffmann A, Dege T, Kunze R, Ernst AS, Lorenz H, Böhler LI, Korff T, Marti HH, Heiland S, Bendszus M, Helluy X, Pham M. Early Blood-Brain Barrier Disruption in Ischemic Stroke Initiates Multifocally Around Capillaries/Venules. Stroke. 2018 May 14. pii: STROKEAHA.118.020927. doi: 10.1161/STROKEAHA.118.020927. [Epub ahead of print]

49.

Hefter D, Marti HH, Gass P, Inta D. Perinatal Hypoxia and Ischemia in Animal Models of Schizophrenia. Front Psychiatry. 2018 Mar 29;9:106. doi: 10.3389/fpsyt.2018.00106. eCollection 2018.

2017

48.

Arif R, Zaradzki M, Remes A, Seppelt P, Kunze R, Schröder H, Schwill S, Ensminger SM, Robinson PN, Karck M, Müller OJ, Hecker M, Wagner AH, Kallenbach K. AP-1 Oligodeoxynucleotides Reduce Aortic Elastolysis in a Murine Model of Marfan Syndrome. Mol Ther Nucleic Acids. 2017 Dec 15; 9: 69–79. Published online 2017 Sep 20. doi: 10.1016/j.omtn.2017.08.014

47.

Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti HH, Ermakova O, Rempel E, Stoeckli ET, Ruiz de Almodóvar C. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017 Mar 6;8:14583. doi: 10.1038/ncomms14583.

46.

Kunze R. Dimethyl fumarate for ischemic stroke. Oncotarget. 2017 Feb 28;8(9):14281-14282. doi: 10.18632/oncotarget.15357.

45.

Marti HH, Kunze R. Oxygen sensors and neuronal adaptation to ischemia. Oncotarget. 2017 Jan 10;8(2):1955-1956. doi: 10.18632/oncotarget.13938.

44.

Barteczek P, Li L, Ernst AS, Böhler LI, Marti HH, Kunze R. Neuronal HIF-1α and HIF-2α deficiency improves neuronal survival and sensorimotor function in the early acute phase after ischemic stroke. J Cereb Blood Flow Metab. 2017 Jan;37(1):291-306. Epub 2016 Jan 8.

2016

43.

Gruneberg D, Montellano FA, Plaschke K, Li L, Marti HH, Kunze R. Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion. Exp Neurol. 2016 Dec;286:93-106. doi: 10.1016/j.expneurol.2016.10.001.

42.

Li L, Saliba P, Reischl S, Marti HH, Kunze R. Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner. Neurobiol Dis. 2016 Jul;91:221-35. doi: 10.1016/j.nbd.2016.03.018. Epub 2016 Mar 19.

41.

Lin-Holderer J, Li L, Gruneberg D, Marti HH, Kunze R. Fumaric acid esters promote neuronal survival upon ischemic stress through activation of the Nrf2 but not HIF-1 signaling pathway. Neuropharmacology. 2016 Jun;105:228-40. doi: 10.1016/j.neuropharm.2016.01.023. Epub 2016 Jan 19.

40.

Hoffmann A, Kunze R, Helluy X, Milford D, Heiland S, Bendszus M, Pham M, Marti HH. High-Field MRI Reveals a Drastic Increase of Hypoxia-Induced Microhemorrhages upon Tissue Reoxygenation in the Mouse Brain with Strong Predominance in the Olfactory Bulb. PLoS One. 2016 Feb 10;11(2):e0148441. doi: 10.1371/journal.pone.0148441. eCollection 2016.


Recent Publications

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Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells. Redox Biol. 2018 Jun;16:113-122. doi: 10.1016/j.redox.2018.02.018. Epub 2018 Mar 1.

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Improving electrical properties of iPSC-cardiomyocytes by enhancing Cx43 expression. J Mol Cell Cardiol. 2018 May 16. pii: S0022-2828(18)30171-8. doi: 10.1016/j.yjmcc.2018.05.010. [Epub ahead of print]

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Early Blood-Brain Barrier Disruption in Ischemic Stroke Initiates Multifocally Around Capillaries/Venules. Stroke. 2018 May 14. pii: STROKEAHA.118.020927. doi: 10.1161/STROKEAHA.118.020927. [Epub ahead of print]

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In silico assessment of the conduction mechanism of the Ryanodine Receptor 1 reveals previously unknown exit pathways. Sci Rep. 2018 May 2;8(1):6886. doi: 10.1038/s41598-018-25061-z.

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Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain. Sci Rep. 2018 Apr 24;8(1):6432. doi: 10.1038/s41598-018-24629-z.

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Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2. Front Mol Neurosci. 2018 Apr 5;11:103. doi: 10.3389/fnmol.2018.00103. eCollection 2018.

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Glycyrrhetinic Acid Antagonizes Pressure-Induced Venous Remodeling in Mice. Front Physiol. 2018 Apr 4;9:320. doi: 10.3389/fphys.2018.00320. eCollection 2018.

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Respiration-Entrained Brain Rhythms Are Global but Often Overlooked. Trends Neurosci. 2018 Apr;41(4):186-197. doi: 10.1016/j.tins.2018.01.007. Epub 2018 Feb 9.

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Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5. FASEB J. 2018 Apr;32(4):2021-2035. doi: 10.1096/fj.201700384RR. Epub 2018 Jan 5.

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VCAM-1 expression is upregulated by CD34+/CD133+-stem cells derived from septic patients. PLoS One. 2018 Mar 30;13(3):e0195064. doi: 10.1371/journal.pone.0195064. eCollection 2018.

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Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal. Cell Physiol Biochem. 2018 Apr;46(2):713-726. doi: 10.1159/000488727. Epub 2018 Mar 29.

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Making room for new memories. Science. 2018 Mar 30;359(6383):1461-1462. doi: 10.1126/science.aat1493.

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Bringing European physiologists together. Acta Physiol (Oxf). 2018 Apr;222(4):e13043. doi: 10.1111/apha.13043. Epub 2018 Feb 15.

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Endothelial progenitor cells accelerate endothelial regeneration in an in vitro model of Shigatoxin-2a-induced injury via soluble growth factors. Am J Physiol Renal Physiol. 2018 Mar 7. doi: 10.1152/ajprenal.00633.2017. [Epub ahead of print]

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Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down-regulated proportionally to neuronal loss in the human epileptic hippocampus. Glia. 2018 May;66(5):920-933. doi: 10.1002/glia.23292. Epub 2018 Jan 19.

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Expansion of functional personalized cells with specific transgene combinations. Nat Commun. 2018 Mar 8;9(1):994. doi: 10.1038/s41467-018-03408-4.


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4035
Fax:+49 6221 54-4038
E-mail:sekretariat.hecker@
physiologie.uni-heidelberg.de