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Institut für Physiologie und Pathophysiologie

Publikationen

 

Ältere Publikationen finden Sie über das Menü in der rechten Spalte.

 

Markierte Titel sind mit dem jeweiligen Abstract auf einer frei zugänglichen externen Webseite verlinkt.

2019

54.

Nasyrov E, Nolan KA, Wenger RH, Marti HH, Kunze R. The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain. FASEB J. 2019 Nov;33(11):12812-12824. doi: 10.1096/fj.201901385RR. Epub 2019 Aug 30.

53.

Park MH, Choi BJ, Jeong MS, Lee JY, Jung IK, Park KH, Lee HW, Yamaguchi T, Marti HH, Lee BH, Schuchman EH, Jin HK, Bae JS. Characterization of the Subventricular-Thalamo-Cortical Circuit in the NP-C Mouse Brain, and New Insights Regarding Treatment. Mol Ther. 2019 Aug 7;27(8):1507-1526. doi: 10.1016/j.ymthe.2019.05.008. Epub 2019 May 16.

52.

Kunze R, Marti HH. Angioneurins-key regulators of blood-brain barrier integrity during hypoxic and ischemic brain injury. Prog Neurobiol. 2019 Jul;178:101611. doi: 10.1016/j.pneurobio.2019.03.004. Epub 2019 Apr 7. Review.

51.

Ernst AS, Böhler LI, Hagenston AM, Hoffmann A, Heiland S, Sticht C, Bendszus M, Hecker M, Bading H, Marti HH, Korff T, Kunze R. EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke. Acta Neuropathol Commun. 2019 Feb 5;7(1):15. doi: 10.1186/s40478-019-0669-7.

2018

50.

Hoffmann A, Dege T, Kunze R, Ernst AS, Lorenz H, Böhler LI, Korff T, Marti HH, Heiland S, Bendszus M, Helluy X, Pham M. Early Blood-Brain Barrier Disruption in Ischemic Stroke Initiates Multifocally Around Capillaries/Venules. Stroke. 2018 Jun;49(6):1479-1487. doi: 10.1161/STROKEAHA.118.020927. Epub 2018 May 14.

49.

Hefter D, Marti HH, Gass P, Inta D. Perinatal Hypoxia and Ischemia in Animal Models of Schizophrenia. Front Psychiatry. 2018 Mar 29;9:106. doi: 10.3389/fpsyt.2018.00106. eCollection 2018.

2017

48.

Arif R, Zaradzki M, Remes A, Seppelt P, Kunze R, Schröder H, Schwill S, Ensminger SM, Robinson PN, Karck M, Müller OJ, Hecker M, Wagner AH, Kallenbach K. AP-1 Oligodeoxynucleotides Reduce Aortic Elastolysis in a Murine Model of Marfan Syndrome. Mol Ther Nucleic Acids. 2017 Dec 15; 9: 69–79. Published online 2017 Sep 20. doi: 10.1016/j.omtn.2017.08.014

47.

Himmels P, Paredes I, Adler H, Karakatsani A, Luck R, Marti HH, Ermakova O, Rempel E, Stoeckli ET, Ruiz de Almodóvar C. Motor neurons control blood vessel patterning in the developing spinal cord. Nat Commun. 2017 Mar 6;8:14583. doi: 10.1038/ncomms14583.

46.

Kunze R. Dimethyl fumarate for ischemic stroke. Oncotarget. 2017 Feb 28;8(9):14281-14282. doi: 10.18632/oncotarget.15357.

45.

Marti HH, Kunze R. Oxygen sensors and neuronal adaptation to ischemia. Oncotarget. 2017 Jan 10;8(2):1955-1956. doi: 10.18632/oncotarget.13938.

44.

Barteczek P, Li L, Ernst AS, Böhler LI, Marti HH, Kunze R. Neuronal HIF-1α and HIF-2α deficiency improves neuronal survival and sensorimotor function in the early acute phase after ischemic stroke. J Cereb Blood Flow Metab. 2017 Jan;37(1):291-306. Epub 2016 Jan 8.

2016

43.

Gruneberg D, Montellano FA, Plaschke K, Li L, Marti HH, Kunze R. Neuronal prolyl-4-hydroxylase 2 deficiency improves cognitive abilities in a murine model of cerebral hypoperfusion. Exp Neurol. 2016 Dec;286:93-106. doi: 10.1016/j.expneurol.2016.10.001.

42.

Li L, Saliba P, Reischl S, Marti HH, Kunze R. Neuronal deficiency of HIF prolyl 4-hydroxylase 2 in mice improves ischemic stroke recovery in an HIF dependent manner. Neurobiol Dis. 2016 Jul;91:221-35. doi: 10.1016/j.nbd.2016.03.018. Epub 2016 Mar 19.

41.

Lin-Holderer J, Li L, Gruneberg D, Marti HH, Kunze R. Fumaric acid esters promote neuronal survival upon ischemic stress through activation of the Nrf2 but not HIF-1 signaling pathway. Neuropharmacology. 2016 Jun;105:228-40. doi: 10.1016/j.neuropharm.2016.01.023. Epub 2016 Jan 19.

40.

Hoffmann A, Kunze R, Helluy X, Milford D, Heiland S, Bendszus M, Pham M, Marti HH. High-Field MRI Reveals a Drastic Increase of Hypoxia-Induced Microhemorrhages upon Tissue Reoxygenation in the Mouse Brain with Strong Predominance in the Olfactory Bulb. PLoS One. 2016 Feb 10;11(2):e0148441. doi: 10.1371/journal.pone.0148441. eCollection 2016.


Aktuell 

 

 

Aufgrund der aktuellen Lage bitten wir, direkte Besuche im Institut so weit wie möglich zu vermeiden. Die MitarbeiterInnen des Instituts für Physiologie und Pathophysiologie sind jedoch weiterhin per E-Mail zu erreichen. 

 

28.02.2020

 

Die Deutsche Physiologische Gesellschaft (DPG) stellt in ihrem im Februar erschienenen Newsletter die jüngste Veröffentlichung der Arbeitsgruppe von Nina Ullrich, Abteilung Herz- und Kreislaufphysiologie, als "Paper of the Month" vor.

 

Silbernagel N, Körner A, Balitzki J, Jaggy M, Bertels S, Richter B, Hippler M, Hellwig A, Hecker M, Bastmeyer M, Ullrich ND. Shaping the heart: Structural and functional maturation of iPSC-cardiomyocytes in 3D-micro-scaffolds. Biomaterials. 2020 Jan;227:119551. doi: 10.1016/j.biomaterials.2019.119551. Epub 2019 Oct 19.

 

Neue Publikationen

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AAV-mediated TIMP-1 overexpression in aortic tissue reduces the severity of allograft vasculopathy in mice. J Heart Lung Transplant. 2020 Apr;39(4):389-398. doi: 10.1016/j.healun.2020.01.1338. Epub 2020 Jan 30.

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Endothelial CD40 Mediates Microvascular von Willebrand Factor-Dependent Platelet Adhesion Inducing Inflammatory Venothrombosis in ADAMTS13 Knockout Mice. Thromb Haemost. 2020 Mar;120(3):466-476. doi: 10.1055/s-0040-1702228. Epub 2020 Mar 5.

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Assembly of vascular smooth muscle cells in 3D aggregates provokes cellular quiescence. Exp Cell Res. 2020 Mar 1;388(1):111782. doi: 10.1016/j.yexcr.2019.111782. Epub 2019 Dec 16.

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Clusters of cooperative ion channels enable a membrane-potential-based mechanism for short-term memory. Elife. 2020 Feb 7;9. pii: e49974. doi: 10.7554/eLife.49974.

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Mepivacaine reduces calcium transients in isolated murine ventricular cardiomyocytes. BMC Anesthesiol. 2020 Jan 8;20(1):10. doi: 10.1186/s12871-019-0926-0.

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Mild metabolic stress is sufficient to disturb the formation of pyramidal cell ensembles during gamma oscillations. J Cereb Blood Flow Metab. 2019 Dec 16:271678X19892657. doi: 10.1177/0271678X19892657. [Epub ahead of print

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Risk and protective factors for post-thrombotic syndrome after deep venous thrombosis. J Vasc Surg Venous Lymphat Disord. 2019 Dec 13. pii: S2213-333X(19)30537-2. doi: 10.1016/j.jvsv.2019.10.012. [Epub ahead of print]

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Amyloid, APP, and Electrical Activity of the Brain. Neuroscientist. 2019 Nov 29:1073858419882619. doi: 10.1177/1073858419882619. [Epub ahead of print]

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The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms. J Cereb Blood Flow Metab. 2019 Nov 13:271678X19887777. doi: 10.1177/0271678X19887777. [Epub ahead of print]

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Functional association of a CD40 gene single nucleotide polymorphism with the pathogenesis of coronary heart disease. Cardiovasc Res. 2019 Aug 2. pii: cvz206. doi: 10.1093/cvr/cvz206. [Epub ahead of print]


Institut für
Physiologie und Pathophysiologie

Universität Heidelberg

Im Neuenheimer Feld 326

69120 Heidelberg

Telefon:+49 6221 54-4056
Telefax:+49 6221 54-6364
E-Mail:susanne.bechtel@
physiologie.uni-heidelberg.de