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Institute of Physiology and Pathophysiology


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Dr. Larissa Pfisterer awarded the Friedrich Reutner-Prize by the Medical Faculty

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Heidelberg University researcher awarded Animal Welfare Prize of the German Research Foundation


  • New methods for vascular research reduce number of experimental animals / Human umbilical cord cells mimic vessel walls

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The vascular system of the mouse ear resembles arms of a river on a map. In transmitted light even smallest blood vessels are apparentb.


Photo: Institute of Physiology and Pathophysiology, Heidelberg University

Prof. Thomas Korff uses cell cultures to investigate pathological remodeling processes in blood vessels.


Photo: Heidelberg University Hospital

At the microscope Prof. Thomas Korff analyzes changes in the vascular system at the cell level.


Photo: Institute of Physiology and Pathophysiology, Heidelberg University

Professor Thomas Korff of the Department of Physiology and Pathophysiology at Heidelberg University, Germany.


Photo: Heidelberg University Hospital



Dissertation Award of the German Hypertension League for Heidelberg Physiologist

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Prof. Markus Hecker elected new president of the Federation of European Physiological Societies

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Article by Suresh Babu et al. is Editors' Choice in the current issue of Science

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Article by Suresh Babu et al. on the cover of the online edition of Science Signaling

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UCB Pharma Prize for Heidelberg physiologists


  • Young scientists at Heidelberg University recognised for their work on the development of varicose veins
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Evelyn Spalek of the team Vascular Medicine of UCB Pharma GmbH in Monheim (l.) and DGA President Prof. Ulrich Hoffmann (r.) presented the prize to Dr. Hannes Schröder and Anja Feldner.


Photo: Harald Auer






Protein causes varicose veins


  • Heidelberg scientists develop model for studying varicose veins / Results published in renowned journal
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Publication by the WG Korff featured on the cover of the FASEB Journal Dies ist ein externer Link

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Recent Publications


Methylglyoxal evokes acute Ca2+ transients in distinct cell types and increases agonist-evoked Ca2+ entry in endothelial cells via CRAC channels. Cell Calcium. 2019 Mar;78:66-75. doi: 10.1016/j.ceca.2019.01.002. Epub 2019 Jan 9.


EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke. Acta Neuropathol Commun. 2019 Feb 5;7(1):15. doi: 10.1186/s40478-019-0669-7.


Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer's disease amyloidosis. PLoS One. 2019 Jan 15;14(1):e0209228. doi: 10.1371/journal.pone.0209228. eCollection 2019.


Medikamentöse Varikosetherapie aus der Perspektive experimenteller Modelle. Praxis (Bern 1994). 2019 Jan;108(1):31-36. doi: 10.1024/1661-8157/a003147.


Selective vulnerability of αOFF retinal ganglion cells during onset of autoimmune optic neuritis. Neuroscience. 2018 Nov 21;393:258-272. doi: 10.1016/j.neuroscience.2018.07.040. Epub 2018 Aug 1.


The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function. FASEB J2018 Nov;32(11):6159-6173. Epub 2018 Jun 7.


Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow- and pressure-induced arterial remodeling in mice. FASEB J. 2018 Nov 1:fj201801594R. doi: 10.1096/fj.201801594R. [Epub ahead of print]


Reduction of Transplant Vasculopathy by Intraoperative Nucleic Acid-based Therapy in a Mouse Aortic Allograft Model. Thorac Cardiovasc Surg. 2018 Oct 23. doi: 10.1055/s-0038-1673633. [Epub ahead of print]

Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg


Phone:+49 6221 54-4035
Fax:+49 6221 54-4038