Select languageSelect language
Institute of Physiology and Pathophysiology

Prof. Dr. rer. nat. Markus Hecker

Heidelberg University

Institute of Physiology and Pathophysiology

Division of Cardiovascular Physiologie

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

phone:

+49 6221 54-4036/4035

fax:

+49 6221 54-4038

e-mail:

hecker@physiologie.uni-heidelberg.de

Curriculum Vitae

2014-2016

Managing Director of the Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2012

Specialist of Physiology (German Physiological Society)

since 2006

Head of the Division of Cardiovascular Physiology, Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2006-2011

Managing Director of the Institute of Physiology and Pathophysiology, Heidelberg University, Germany

since 2004

Full Professor (C4) and Director, Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2001-2003

Managing partner, AVONTEC GmbH, Göttingen, Germany

1996-2004

Full Professor (C3) and Head, Department of Cardiovascular Physiology, Göttingen University, Germany

1993-1996

Assistant Professor in the Department of Cardiovascular Physiology, University of Frankfurt, Germany

1993

State doctorate (Dr. rer. nat., habil. in Physiology), Faculty of Medicine, University of Freiburg, Germany

1993

Specialist of Pharmacology (German Society of Experimental and Clinical Pharmacology and Toxicology)

1991-1993

Lecturer in the Department of Applied Physiology, University of Freiburg, Germany

1990-1991

Senior Scientist and Honorary Lecturer, William Harvey Research Institute, St. Bartholomew’s Hospital Medical College, London, UK

1989-1990

Postdoc, William Harvey Research Institute, St. Bartholomew’s Hospital Medical College, London, UK

1988-1989

Postdoc, Department of Physiology and Biophysics, Georgetown University, Washington, DC, USA

1988

Dr. rer. nat. (Ph. D. in Biochemical Pharmacology), University of Konstanz, Germany

1986-1989

Post-graduate in the Research Training Group Biochemical Pharmacology, University of Konstanz, Germany

1985

Diploma (M. Sc. in Biology), University of Konstanz, Germany

1980-1985

Study of Biology, University of Konstanz, Germany

Honors and Awards

2003

German Founders Award in the category "Concept" (together with G. Hasenfuss)

2000

Wulf Vater-Dihydropyridine Research Award, Wulf Vater-Foundation (together with M. Cattaruzza, R. Wachter and A.H. Wagner)

1994

Award of the Dr. Heinz und Helene Adam-Foundation for Research on Human Blood and Lymph Vessels

1993

Sandoz Award for therapy-related pharmacological research, German Societey for Experimental and Clinical Pharmacology (togehter with R. Busse, W. Linz and G. Wiemer)


Recent Publications

*

Early Blood-Brain Barrier Disruption in Ischemic Stroke Initiates Multifocally Around Capillaries/Venules. Stroke. 2018 May 14. pii: STROKEAHA.118.020927. doi: 10.1161/STROKEAHA.118.020927. [Epub ahead of print]

*

Impact of carbonylation on glutathione peroxidase-1 activity in human hyperglycemic endothelial cells. Redox Biol. 2018 Jun;16:113-122. doi: 10.1016/j.redox.2018.02.018. Epub 2018 Mar 1.

*

In silico assessment of the conduction mechanism of the Ryanodine Receptor 1 reveals previously unknown exit pathways. Sci Rep. 2018 May 2;8(1):6886. doi: 10.1038/s41598-018-25061-z.

*

Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain. Sci Rep. 2018 Apr 24;8(1):6432. doi: 10.1038/s41598-018-24629-z.

*

Stability and Function of Hippocampal Mossy Fiber Synapses Depend on Bcl11b/Ctip2. Front Mol Neurosci. 2018 Apr 5;11:103. doi: 10.3389/fnmol.2018.00103. eCollection 2018.

*

Glycyrrhetinic Acid Antagonizes Pressure-Induced Venous Remodeling in Mice. Front Physiol. 2018 Apr 4;9:320. doi: 10.3389/fphys.2018.00320. eCollection 2018.

*

Respiration-Entrained Brain Rhythms Are Global but Often Overlooked. Trends Neurosci. 2018 Apr;41(4):186-197. doi: 10.1016/j.tins.2018.01.007. Epub 2018 Feb 9.

*

Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5. FASEB J. 2018 Apr;32(4):2021-2035. doi: 10.1096/fj.201700384RR. Epub 2018 Jan 5.

*

VCAM-1 expression is upregulated by CD34+/CD133+-stem cells derived from septic patients. PLoS One. 2018 Mar 30;13(3):e0195064. doi: 10.1371/journal.pone.0195064. eCollection 2018.

*

Carnosine Catalyzes the Formation of the Oligo/Polymeric Products of Methylglyoxal. Cell Physiol Biochem. 2018;46(2):713-726. doi: 10.1159/000488727. Epub 2018 Mar 29.

*

Making room for new memories. Science. 2018 Mar 30;359(6383):1461-1462. doi: 10.1126/science.aat1493.

*

Bringing European physiologists together. Acta Physiol (Oxf). 2018 Apr;222(4):e13043. doi: 10.1111/apha.13043. Epub 2018 Feb 15.

*

Endothelial progenitor cells accelerate endothelial regeneration in an in vitro model of Shigatoxin-2a-induced injury via soluble growth factors. Am J Physiol Renal Physiol. 2018 Mar 7. doi: 10.1152/ajprenal.00633.2017. [Epub ahead of print]

*

Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down-regulated proportionally to neuronal loss in the human epileptic hippocampus. Glia. 2018 May;66(5):920-933. doi: 10.1002/glia.23292. Epub 2018 Jan 19.

*

Expansion of functional personalized cells with specific transgene combinations. Nat Commun. 2018 Mar 8;9(1):994. doi: 10.1038/s41467-018-03408-4.


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4035
Fax:+49 6221 54-4038
E-mail:sekretariat.hecker@
physiologie.uni-heidelberg.de