Select languageSelect language
Institute of Physiology and Pathophysiology

Prof. Dr. rer. nat. Markus Hecker

Heidelberg University

Institute of Physiology and Pathophysiology

Department of Cardiovascular Physiologie

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

phone:

+49 6221 54-4036/4035

fax:

+49 6221 54-4038

e-mail:

hecker@physiologie.uni-heidelberg.de

Curriculum Vitae

2014-2016

Managing Director of the Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2012

Specialist of Physiology (German Physiological Society)

since 2006

Head of the Division of Cardiovascular Physiology, Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2006-2011

Managing Director of the Institute of Physiology and Pathophysiology, Heidelberg University, Germany

since 2004

Full Professor (C4) and Director, Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2001-2003

Managing partner, AVONTEC GmbH, Göttingen, Germany

1996-2004

Full Professor (C3) and Head, Department of Cardiovascular Physiology, Göttingen University, Germany

1993-1996

Assistant Professor in the Department of Cardiovascular Physiology, University of Frankfurt, Germany

1993

State doctorate (Dr. rer. nat., habil. in Physiology), Faculty of Medicine, University of Freiburg, Germany

1993

Specialist of Pharmacology (German Society of Experimental and Clinical Pharmacology and Toxicology)

1991-1993

Lecturer in the Department of Applied Physiology, University of Freiburg, Germany

1990-1991

Senior Scientist and Honorary Lecturer, William Harvey Research Institute, St. Bartholomew’s Hospital Medical College, London, UK

1989-1990

Postdoc, William Harvey Research Institute, St. Bartholomew’s Hospital Medical College, London, UK

1988-1989

Postdoc, Department of Physiology and Biophysics, Georgetown University, Washington, DC, USA

1988

Dr. rer. nat. (Ph. D. in Biochemical Pharmacology), University of Konstanz, Germany

1986-1989

Post-graduate in the Research Training Group Biochemical Pharmacology, University of Konstanz, Germany

1985

Diploma (M. Sc. in Biology), University of Konstanz, Germany

1980-1985

Study of Biology, University of Konstanz, Germany

Honors and Awards

2003

German Founders Award in the category "Concept" (together with G. Hasenfuss)

2000

Wulf Vater-Dihydropyridine Research Award, Wulf Vater-Foundation (together with M. Cattaruzza, R. Wachter and A.H. Wagner)

1994

Award of the Dr. Heinz und Helene Adam-Foundation for Research on Human Blood and Lymph Vessels

1993

Sandoz Award for therapy-related pharmacological research, German Societey for Experimental and Clinical Pharmacology (togehter with R. Busse, W. Linz and G. Wiemer)


Recent Publications

*

The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms. J Cereb Blood Flow Metab. 2019 Nov 13:271678X19887777. doi: 10.1177/0271678X19887777. [Epub ahead of print]

*

Shaping the heart: Structural and functional maturation of iPSC-cardiomyocytes in 3D-micro-scaffolds. Biomaterials. 2020 Jan;227:119551. doi: 10.1016/j.biomaterials.2019.119551. Epub 2019 Oct 19.

*

Simulation Strategies for Calcium Microdomains and Calcium Noise. Adv Exp Med Biol. 2020;1131:771-797. doi: 10.1007/978-3-030-12457-1_31.

*

Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer. Int J Cancer. 2019 Dec 15;145(12):3299-3310. doi: 10.1002/ijc.32481. Epub 2019 Jun 19.

*

Persistent increase in ventral hippocampal long-term potentiation by juvenile stress: A role for astrocytic glutamine synthetase. Glia. 2019 Dec;67(12):2279-2293. doi: 10.1002/glia.23683. Epub 2019 Jul 17.

*

4.2 Kreislauf. In: Physiologie hoch2 (Gründer S, Schlüter KD, eds.) Urban & Fischer Verlag/Elsevier GmbH 2019, pp. 192-225. ISBN 978-3-437-43461-7

*

The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain. FASEB J. 2019 Nov;33(11):12812-12824. doi: 10.1096/fj.201901385RR. Epub 2019 Aug 30.

*

TRPC channels are not required for graded persistent activity in entorhinal cortex neurons. Hippocampus. 2019 Nov;29(11):1038-1048. doi: 10.1002/hipo.23094. Epub 2019 Apr 19.

*

The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease. Biochem Biophys Res Commun. 2019 Oct 29;519(1):141-147. doi: 10.1016/j.bbrc.2019.08.150. Epub 2019 Aug 31.

*

Endothelial cell modulation of cardiomyocyte gene expression. Exp Cell Res. 2019 Oct 15;383(2):111565. doi: 10.1016/j.yexcr.2019.111565. Epub 2019 Aug 20.

*

Pacemaker cell characteristics of differentiated and HCN4-transduced human mesenchymal stem cells. Life Sci. 2019 Sep 1;232:116620. doi: 10.1016/j.lfs.2019.116620. Epub 2019 Jul 7.

*

Reduction of Transplant Vasculopathy by Intraoperative Nucleic Acid-based Therapy in a Mouse Aortic Allograft Model. Thorac Cardiovasc Surg. 2019 Sep;67(6):503-512. doi: 10.1055/s-0038-1673633. Epub 2018 Oct 23.

*

Functional association of a CD40 gene single nucleotide polymorphism with the pathogenesis of coronary heart disease. Cardiovasc Res. 2019 Aug 2. pii: cvz206. doi: 10.1093/cvr/cvz206. [Epub ahead of print]


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4035
Fax:+49 6221 54-4038
E-mail:sekretariat.hecker@
physiologie.uni-heidelberg.de