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Institute of Physiology and Pathophysiology

Prof. Dr. rer. nat. Markus Hecker

Heidelberg University

Institute of Physiology and Pathophysiology

Division of Cardiovascular Physiologie

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

phone:

+49 6221 54-4036/4035

fax:

+49 6221 54-4038

e-mail:

hecker@physiologie.uni-heidelberg.de

Curriculum Vitae

2014-2016

Managing Director of the Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2012

Specialist of Physiology (German Physiological Society)

since 2006

Head of the Division of Cardiovascular Physiology, Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2006-2011

Managing Director of the Institute of Physiology and Pathophysiology, Heidelberg University, Germany

since 2004

Full Professor (C4) and Director, Institute of Physiology and Pathophysiology, Heidelberg University, Germany

2001-2003

Managing partner, AVONTEC GmbH, Göttingen, Germany

1996-2004

Full Professor (C3) and Head, Department of Cardiovascular Physiology, Göttingen University, Germany

1993-1996

Assistant Professor in the Department of Cardiovascular Physiology, University of Frankfurt, Germany

1993

State doctorate (Dr. rer. nat., habil. in Physiology), Faculty of Medicine, University of Freiburg, Germany

1993

Specialist of Pharmacology (German Society of Experimental and Clinical Pharmacology and Toxicology)

1991-1993

Lecturer in the Department of Applied Physiology, University of Freiburg, Germany

1990-1991

Senior Scientist and Honorary Lecturer, William Harvey Research Institute, St. Bartholomew’s Hospital Medical College, London, UK

1989-1990

Postdoc, William Harvey Research Institute, St. Bartholomew’s Hospital Medical College, London, UK

1988-1989

Postdoc, Department of Physiology and Biophysics, Georgetown University, Washington, DC, USA

1988

Dr. rer. nat. (Ph. D. in Biochemical Pharmacology), University of Konstanz, Germany

1986-1989

Post-graduate in the Research Training Group Biochemical Pharmacology, University of Konstanz, Germany

1985

Diploma (M. Sc. in Biology), University of Konstanz, Germany

1980-1985

Study of Biology, University of Konstanz, Germany

Honors and Awards

2003

German Founders Award in the category "Concept" (together with G. Hasenfuss)

2000

Wulf Vater-Dihydropyridine Research Award, Wulf Vater-Foundation (together with M. Cattaruzza, R. Wachter and A.H. Wagner)

1994

Award of the Dr. Heinz und Helene Adam-Foundation for Research on Human Blood and Lymph Vessels

1993

Sandoz Award for therapy-related pharmacological research, German Societey for Experimental and Clinical Pharmacology (togehter with R. Busse, W. Linz and G. Wiemer)


Recent Publications

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Chronic hypoxia changes gene expression profile of primary rat carotid body cells: consequences on the expression of NOS isoforms and ET-1 receptors. Physiol Genomics. 2019 Mar 1. doi: 10.1152/physiolgenomics.00114.2018. [Epub ahead of print]

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Priming of microglia with IFN-γ slows neuronal gamma oscillations in situ. Proc Natl Acad Sci U S A. 2019 Feb 19. pii: 201813562. doi: 10.1073/pnas.1813562116. [Epub ahead of print]

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Methylglyoxal evokes acute Ca2+ transients in distinct cell types and increases agonist-evoked Ca2+ entry in endothelial cells via CRAC channels. Cell Calcium. 2019 Mar;78:66-75. doi: 10.1016/j.ceca.2019.01.002. Epub 2019 Jan 9.

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EphB2-dependent signaling promotes neuronal excitotoxicity and inflammation in the acute phase of ischemic stroke. Acta Neuropathol Commun. 2019 Feb 5;7(1):15. doi: 10.1186/s40478-019-0669-7.

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Early alterations in hippocampal perisomatic GABAergic synapses and network oscillations in a mouse model of Alzheimer's disease amyloidosis. PLoS One. 2019 Jan 15;14(1):e0209228. doi: 10.1371/journal.pone.0209228. eCollection 2019.

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Medikamentöse Varikosetherapie aus der Perspektive experimenteller Modelle. Praxis (Bern 1994). 2019 Jan;108(1):31-36. doi: 10.1024/1661-8157/a003147.

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Selective vulnerability of αOFF retinal ganglion cells during onset of autoimmune optic neuritis. Neuroscience. 2018 Nov 21;393:258-272. doi: 10.1016/j.neuroscience.2018.07.040. Epub 2018 Aug 1.

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The VAMP-associated protein VAPB is required for cardiac and neuronal pacemaker channel function. FASEB J2018 Nov;32(11):6159-6173. Epub 2018 Jun 7.

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Genetic ablation of NFAT5/TonEBP in smooth muscle cells impairs flow- and pressure-induced arterial remodeling in mice. FASEB J. 2018 Nov 1:fj201801594R. doi: 10.1096/fj.201801594R. [Epub ahead of print]

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Reduction of Transplant Vasculopathy by Intraoperative Nucleic Acid-based Therapy in a Mouse Aortic Allograft Model. Thorac Cardiovasc Surg. 2018 Oct 23. doi: 10.1055/s-0038-1673633. [Epub ahead of print]


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4035
Fax:+49 6221 54-4038
E-mail:sekretariat.hecker@
physiologie.uni-heidelberg.de