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Institute of Physiology and Pathophysiology

Institute of Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

 

 

Managing Director

 

Prof. Dr. Andreas Draguhn

 

Phone:

+49 6221 54-4057

Fax:

+49 6221 54-6364

E-Mail:

andreas.draguhn@physiologie.uni-heidelberg.de

 


Secretary: Susanne Bechtel

 

Phone:

+49 6221 54-4056

Fax:

+49 6221 54-6364

E-Mail:

susanne.bechtel@physiologie.uni-heidelberg.de

 

 

 

 

Deputy Managing Director

 

Prof. Dr. Markus Hecker

 

Phone:

+49 6221 54-4036

Fax:

+49 6221 54-4038

E-Mail:

hecker@physiologie.uni-heidelberg.de

The Institute for Physiology and Pathophysiology is a scientific institution assigned to the Faculty of Medicine of Heidelberg University. Its tasks are education and research in physiology.

 

About 80 people work in two departments, headed by the Professors Dr. Andreas Draguhn and Dr. Markus Hecker, their associated independent working groups lead by the Professors Dr. Alexander Groh, Dr. Oliver Kann and Dr. Hugo Marti, respectively, and the administration.

 

Members of the institute jointly teach lecture and lab courses in physiology for the approximately 450 students of medicine and dentistry admitted annually to Heidelberg University.

 

 

The short animated video "What is physiology" produced by The Physiological Society (UK) gives a brief introduction into the field of physiology. To watch the video on the society's YouTube channel click here.Dies ist ein externer Link

by kind permission of The Physiological Society (UK)Dies ist ein externer Link


Recent Publications

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Mepivacaine reduces calcium transients in isolated murine ventricular cardiomyocytes. BMC Anesthesiol. 2020 Jan 8;20(1):10. doi: 10.1186/s12871-019-0926-0.

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Factors determining microbial colonization of liquid nitrogen storage tanks used for archiving biological samples. Appl Microbiol Biotechnol. 2020 Jan;104(1):131-144. doi: 10.1007/s00253-019-10242-1. Epub 2019 Nov 28.

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Shaping the heart: Structural and functional maturation of iPSC-cardiomyocytes in 3D-micro-scaffolds. Biomaterials. 2020 Jan;227:119551. doi: 10.1016/j.biomaterials.2019.119551. Epub 2019 Oct 19.

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Simulation Strategies for Calcium Microdomains and Calcium Noise. Adv Exp Med Biol. 2020;1131:771-797. doi: 10.1007/978-3-030-12457-1_31.

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Tyrphostin AG490 reduces inflammation and fibrosis in neonatal obstructive nephropathy. PLoS One. 2019 Dec 17;14(12):e0226675. doi: 10.1371/journal.pone.0226675. eCollection 2019.

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Assembly of vascular smooth muscle cells in 3D aggregates provokes cellular quiescence. Exp Cell Res. 2019 Dec 16:111782. doi: 10.1016/j.yexcr.2019.111782. [Epub ahead of print]

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Mild metabolic stress is sufficient to disturb the formation of pyramidal cell ensembles during gamma oscillations. J Cereb Blood Flow Metab. 2019 Dec 16:271678X19892657. doi: 10.1177/0271678X19892657. [Epub ahead of print

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Risk and protective factors for post-thrombotic syndrome after deep venous thrombosis. J Vasc Surg Venous Lymphat Disord. 2019 Dec 13. pii: S2213-333X(19)30537-2. doi: 10.1016/j.jvsv.2019.10.012. [Epub ahead of print]

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AAV-Mediated Expression of AP-1-Neutralizing RNA Decoy Oligonucleotides Attenuates Transplant Vasculopathy in Mouse Aortic Allografts. Mol Ther Methods Clin Dev. 2019 Oct 2;15:246-256. doi: 10.1016/j.omtm.2019.09.009. eCollection 2019 Dec 13.

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Amyloid, APP, and Electrical Activity of the Brain. Neuroscientist. 2019 Nov 29:1073858419882619. doi: 10.1177/1073858419882619. [Epub ahead of print]

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The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms. J Cereb Blood Flow Metab. 2019 Nov 13:271678X19887777. doi: 10.1177/0271678X19887777. [Epub ahead of print]

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Somatic mutations and promotor methylation of the ryanodine receptor 2 is a common event in the pathogenesis of head and neck cancer. Int J Cancer. 2019 Dec 15;145(12):3299-3310. doi: 10.1002/ijc.32481. Epub 2019 Jun 19.

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Loss of the serine protease HTRA1 impairs smooth muscle cells maturation. Sci Rep. 2019 Dec 3;9(1):18224. doi: 10.1038/s41598-019-54807-6.

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Persistent increase in ventral hippocampal long-term potentiation by juvenile stress: A role for astrocytic glutamine synthetase. Glia. 2019 Dec;67(12):2279-2293. doi: 10.1002/glia.23683. Epub 2019 Jul 17.

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The neuronal oxygen-sensing pathway controls postnatal vascularization of the murine brain. FASEB J. 2019 Nov;33(11):12812-12824. doi: 10.1096/fj.201901385RR. Epub 2019 Aug 30.

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TRPC channels are not required for graded persistent activity in entorhinal cortex neurons. Hippocampus. 2019 Nov;29(11):1038-1048. doi: 10.1002/hipo.23094. Epub 2019 Apr 19.

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The C-terminal HCN4 variant P883R alters channel properties and acts as genetic modifier of atrial fibrillation and structural heart disease. Biochem Biophys Res Commun. 2019 Oct 29;519(1):141-147. doi: 10.1016/j.bbrc.2019.08.150. Epub 2019 Aug 31.

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Functional association of a CD40 gene single nucleotide polymorphism with the pathogenesis of coronary heart disease. Cardiovasc Res. 2019 Aug 2. pii: cvz206. doi: 10.1093/cvr/cvz206. [Epub ahead of print]


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4056
Fax:+49 6221 54-6364
E-mail:susanne.bechtel@
physiologie.uni-heidelberg.de