Select languageSelect language
Institut für Physiologie und Pathophysiologie

Introduction

The Medical Biophysics Group at the Institute of Physiology and Pathophysiology  was founded in 1990 by Rainer H.A. Fink when he came from the University of Adelaide to take up his professorship in Heidelberg.

 

The work of the group covers various research areas in the fields of physiology, biophysics and basic clinical research. The interdisciplinarity is borne by researchers from various fields of natural and medical sciences, including physicians, physicists, chemists and clinical doctors.

 

Teaching is covered for medical students in physiology and in molecular physiology and biophysics for advanced medical students and students graduating in natural sciences. For interested students it is possible to carry out a PhD thesis in medicine (Dr. med. or Dr. Sc. hum.), a PhD thesis in physics, or a Master's (Diplom) thesis in physics.


Neue Publikationen

*

Effects of the GABA-uptake blocker NNC-711 on spontaneous sharp wave-ripple complexes in mouse hippocampal slices. Hippocampus. 2013 May;23(5):323-9. doi: 10.1002/hipo.22104. Epub 2013 Mar 5.

*

Neuronal expression of glucosylceramide synthase in central nervous system regulates body weight and energy homeostasis. PLoS Biol. 2013 Mar;11(3):e1001506. doi: 10.1371/journal.pbio.1001506. Epub 2013 Mar 12.

*

The tetraspanin network modulates MT1-MMP cell surface trafficking. Int J Biochem Cell Biol. 2013 Mar 9. doi:pii: S1357-2725(13)00067-8. 10.1016/j.biocel.2013.02.020. [Epub ahead of print]

*

Establishment of a Secondary Screening Assay for P/Q-type Calcium Channel Blockers. Comb Chem High Throughput Screen. 2013 Mar 1;16(3):233-43.

*

Synthetic Aβ oligomers (Aβ(1-42) globulomer) modulate presynaptic calcium currents: Prevention of Aβ-induced synaptic deficits by calcium channel blockers. Eur J Pharmacol. 2013 Feb 28;702(1-3):44-55. doi: 10.1016/j.ejphar.2013.01.030. Epub 2013 Jan 30.

*

Oxygen consumption rates during three different neuronal activity states in the hippocampal CA3 network. J Cereb Blood Flow Metab. 2013 Feb;33(2):263-71. doi: 10.1038/jcbfm.2012.165. Epub 2012 Nov 21.

*

Global slowing of network oscillations in mouse neocortex by diazepam. Neuropharmacology. 2013 Feb;65:123-133. doi: 10.1016/j.neuropharm.2012.09.014. Epub 2012 Oct 9.

*

Dysregulation of Hypoxia-Inducible Factor by Presenilin/γ-Secretase Loss-of-Function Mutations. J Neurosci. 2013 Jan 30;33(5):1915-26. doi: 10.1523/JNEUROSCI.3402-12.2013.

*

Hibernating squirrel muscle activates the endurance exercise pathway despite prolonged immobilization. Exp Neurol. 2013 Jan 16. doi:pii: S0014-4886(13)00018-6. 10.1016/j.expneurol.2013.01.005. [Epub ahead of print]

*

Altered HCN4 channel C-linker interaction is associated with familial tachycardia-bradycardia syndrome and atrial fibrillation. Eur Heart J. 2012 Nov 23. [Epub ahead of print]

*

Development of coherent neuronal activity patterns in mammalian cortical networks: common principles and local hetereogeneity. Mech Dev. 2012 Sep 29. pii: S0925-4773(12)00091-3. doi: 10.1016/j.mod.2012.09.006. [Epub ahead of print]


Institut für
Physiologie und Pathophysiologie

Universität Heidelberg

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Telefon:+49 6221 54-4056
Telefax:+49 6221 54-6364
E-Mail:physiologie@uni-hd.de