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Institute of Physiology and Pathophysiology

Prof. Dr. med. Oliver Kann

Heidelberg University

Institute of Physiologie and Pathophysiology

Kann Lab

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

phone:

+49 6221 54-4560

fax:

+49 6221 54-6364

e-mail:

oliver.kann@physiologie.uni-heidelberg.de

  Selected talks

2018

"Microglia activation and neuronal dysfunction", Neurosciences in Intensive Care International Symposium (NICIS), Institut Pasteur, Paris, France

2016

"Bioenergetis of fast neuronal network oscillations", Symposium on Brain Bioenergetis: From Behavior to Pathology, Brain Mind Institute, EPFL, Lausanne, Switzerland

2014

"Energy metabolism and K+-homeostatis during fast neuronal network oscillations", The 11th International Conference on Brain Energy Metabolism, Helsinge, Denmark

2014

"Bioenergetics of fast network oscillations", 1st International Bordeaux Neurocampus/Brain Conference, Bordeaux University, Bordeaux, France

 

 Curriculum vitae

since 2010

Full Professor for General Neurophysiology (W3), Medical Faculty Heidelberg, Ruprecht-Karls-University, Germany

2009

Habilitation and venia legendi for Physiology, Charité-Universitätsmedizin Berlin, Germany

2005-2006

Guest scientist, Department of Neurobiology, Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel 

2004-2010

Senior Research Assistent, Neuronal Mitochondria Research Group (PI), Institute for Neurophysiology, Charité-Universitätsmedizin Berlin 

2003

Licence to practise medicine

2001

Conferral of doctorate (MD), Humboldt-University of Berlin 

2000-2004

Research Assistent, Institute for Neurophysiology and Department of  Neurology, Charité, Humboldt-University of Berlin, Germany

2000

State examination (Staatsexamen) in Human Medicine 

1999

Medical internship (internal medicine, surgery and neurology)

1996-1998

Experimental work for dissertation, Department of Cellular Neurosciences, Max-Delbrück-Center for Molecular Medicine, Berlin-Buch, Germany

1992-2000

Studies of Human Medicine and Philosophy, Philipps-University of Marburg and Free-University of Berlin, Germany

Honors and Awards

2010

Teaching award of reformed curriculum, Charité-Universitätsmedizin Berlin 

2008

Poster award, Gordon Research Conference (Andover, USA) 

2006

Poster award, Gordon Research Conference (Oxford, UK) 

2005

Minerva Short-Term Research Grant (Max-Planck-Society)

1996

Scholarship by GRK-238 (German Research Foundation)


Recent Publications

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Alterations of distributed neuronal network oscillations during acute pain in freely-moving mice. IBRO Rep. 2020 Dec;9:195-206. doi: 10.1016/j.ibror.2020.08.001. eCollection 2020 Dec. Epub 2020 Aug 11.

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Neuronal gamma oscillations and activity-dependent potassium transients remain regular after depletion of microglia in postnatal cortex tissue. J Neurosci Res. 2020 Oct;98(10):1953-1967. doi: 10.1002/jnr.24689. Epub 2020 Jul 7.

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Synchronicity of excitatory inputs drives hippocampal networks to distinct oscillatory patterns. Hippocampus. 2020 Oct;30(10):1044-1057. doi: 10.1002/hipo.23214. Epub 2020 May 15.

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Multifunctional reactive MALDI matrix enabling high-lateral resolution dual polarity MS imaging and lipid C=C position-resolved MS2 imaging. Anal Chem. 2020 Sep 12. doi: 10.1021/acs.analchem.0c03150. Online ahead of print.

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VEGF-D Downregulation in CA1 Pyramidal Neurons Exerts Asymmetric Changes of Dendritic Morphology without Correlated Electrophysiological Alterations. Neuroscience. 2020 Sep 10:S0306-4522(20)30578-9. doi: 10.1016/j.neuroscience.2020.09.012. Online ahead of print.

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Anesthetics and plants: no pain, no brain, and therefore no consciousness. Protoplasma. 2020 Sep 2. doi: 10.1007/s00709-020-01550-9. Online ahead of print.

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Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing. Nat Rev Drug Discov. 2020 Sep;19(9):609-633. doi: 10.1038/s41573-020-0072-x. Epub 2020 Jul 24.

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Microglia and lipids: how metabolism controls brain innate immunity. Semin Cell Dev Biol. 2020 Aug 14;S1084-9521(19)30197-1. doi: 10.1016/j.semcdb.2020.08.001. Online ahead of print.

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GM-CSF induces noninflammatory proliferation of microglia and disturbs electrical neuronal network rhythms in situ. J Neuroinflammation. 2020 Aug 11;17(1):235. doi: 10.1186/s12974-020-01903-4.

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Inhibition of cardiac Kv4.3 (Ito) channel isoforms by class I antiarrhythmic drugs lidocaine and mexiletine. Eur J Pharmacol. 2020 Aug 5;880:173159. doi: 10.1016/j.ejphar.2020.173159. Epub 2020 Apr 29.

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Selective inhibition of mitochondrial respiratory complexes controls the transition of microglia into a neurotoxic phenotype in situ. Brain Behav Immun. 2020 Aug;88:802-814. doi: 10.1016/j.bbi.2020.05.052. Epub 2020 May 21.

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Lactate Attenuates Synaptic Transmission and Affects Brain Rhythms Featuring High Energy Expenditure. iScience. 2020 Jul 24;23(7):101316. doi: 10.1016/j.isci.2020.101316. Epub 2020 Jun 27.

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A Global Cndp1-Knock-Out Selectively Increases Renal Carnosine and Anserine Concentrations in an Age- and Gender-Specific Manner in Mice. Int J Mol Sci. 2020 Jul 10;21(14):4887. doi:10.3390/ijms21144887.

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Mild metabolic stress is sufficient to disturb the formation of pyramidal cell ensembles during gamma oscillations. J Cereb Blood Flow Metab. 2019 Dec 16:271678X19892657. doi: 10.1177/0271678X19892657. [Epub ahead of print

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The mitochondrial calcium uniporter is crucial for the generation of fast cortical network rhythms. J Cereb Blood Flow Metab. 2019 Nov 13:271678X19887777. doi: 10.1177/0271678X19887777. [Epub ahead of print]


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4056
Fax:+49 6221 54-6364
E-mail:susanne.bechtel@
physiologie.uni-heidelberg.de