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Institute of Physiology and Pathophysiology

WG Medical Biophysics

The working group"Medical Biophysics" has been discontinued with the retirement of Prof. Dr. Fink. A new group will be established within the division of Neuro- and Sensory Physiology.

 

 

Head

 

Prof. Dr. rer. nat. Rainer H. A. Fink

 

Phone:

+49 6221 54-4065

Fax:

+49 6221 54-4123

E-Mail:

rainer.fink@physiologie.uni-heidelberg.de

Our Field of Research

The scope of our laboratory covers a wide range of recent and classical techniques for molecular and cellular studies:

  

Main subject of research:

mammalian skeletal muscle

Study muscle diseases:

Duchenne dystrophy with miniDys and mdx mouse models

Critical illness:

myopathy

 

Exchange Programme

The group collaborates with the lab of Prof. Wolfgang Fischer Dies ist ein externer Link at the National Yang-Ming University Dies ist ein externer Link in Taiwan within the framework of an exchange programme in the areas of neuroscience, bioinformatics, biophysics and biotechnology. 

 

A list of all exchange programmes at Heidelberg University can be found here.

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Recent Publications

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Respiration-Entrained Brain Rhythms Are Global but Often Overlooked. Trends Neurosci. 2018 Feb 8. pii: S0166-2236(18)30031-6. doi: 10.1016/j.tins.2018.01.007. [Epub ahead of print] Review.

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Modulation of glutathione peroxidase activity by age-dependent carbonylation in glomeruli of diabetic mice. J Diabetes Complications. 2018 Feb;32(2):130-138. doi: 10.1016/j.jdiacomp.2017.11.007. Epub 2017 Nov 22.

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Bringing European physiologists together. Acta Physiol (Oxf). 2018 Jan 29. doi: 10.1111/apha.13043. [Epub ahead of print]

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Astrocytic glutamine synthetase is expressed in the neuronal somatic layers and down-regulated proportionally to neuronal loss in the human epileptic hippocampus. Glia. 2018 Jan 19. doi: 10.1002/glia.23292. [Epub ahead of print]

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Role of protein carbonylation in diabetes. J Inherit Metab Dis. 2018 Jan;41(1):29-38. doi: 10.1007/s10545-017-0104-9. Epub 2017 Nov 6.

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Sensitive mass spectrometric assay for determination of 15-deoxy-Δ12,14-prostaglandin J2 and its application in human plasma samples of patients with diabetes. Anal Bioanal Chem. 2018 Jan;410(2):521-528. doi: 10.1007/s00216-017-0748-1. Epub 2017 Nov 16.

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Magnolol inhibits venous remodeling in mice. Sci Rep. 2017 Dec 19;7(1):17820. doi: 10.1038/s41598-017-17910-0.

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Hypertension-evoked RhoA activity in vascular smooth muscle cells requires RGS5. FASEB J. 2017 Dec 5. pii: fj.201700384RR. doi: 10.1096/fj.201700384RR. [Epub ahead of print]

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AP-1 Oligodeoxynucleotides Reduce Aortic Elastolysis in a Murine Model of Marfan Syndrome. Mol Ther Nucleic Acids. 2017 Dec 15;9:69-79. doi: 10.1016/j.omtn.2017.08.014. Epub 2017 Sep 20.

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Allosteric inhibition of carnosinase (CN1) by inducing a conformational shift. J Enzyme Inhib Med Chem. 2017 Dec;32(1):1102-1110. doi: 10.1080/14756366.2017.1355793.

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Transcription factor decoy technology: a therapeutic update. Biochem Pharmacol. 2017 Nov 15;144:29-34. doi: 10.1016/j.bcp.2017.06.122. Epub 2017 Jun 19. Review.


Institute of
Physiology and Pathophysiology

Heidelberg University

Im Neuenheimer Feld 326

69120 Heidelberg

Germany

Phone:+49 6221 54-4035
Fax:+49 6221 54-4038
E-mail:sekretariat.hecker@
physiologie.uni-heidelberg.de