RESEARCH SUMMARY

Autophagy disorders have shown to prominently affect the brain in ageing and
disease. Membrane-binding proteins in autophagosomes (AVs) use specialised
motifs to induce and stabilise diverse membrane curvatures and mechanically
drive the transition into characteristic cup-shaped vesicles. My work aims on
elucidating how membrane-shaping proteins could act as master regulators of
autophagosome sorting, shaping, and fusion.

 

CURRICULUM VITAE

2018 Bachelor of Science in Molekular Medizin, University of Tübingen, Germany
2020 Master of Science in moleculare medicine, University of Tübingen, Germany
2025 PhD in Biochemistry, University of Jena, Germany
since 2025 Postdoc, Institute for Anatomy and cell Biology, Dept. Medical Cell Biology, University of Heidelberg, Germany

PUBLICATIONS
 

Englisch AS, Hofbrucker-MacKenzie SA, Izadi-Seitz M, Kessels MM, Qualmann B.
Ankrd26 is a retinoic acid-responsive plasma membrane-binding and -shaping
protein critical for proper cell differentiation. Cell Rep. 2024 Mar 26;43(3):113939. doi:
10.1016/j.celrep.2024.113939. Epub 2024 Mar 16. PMID: 38493476.

Hempel L, Molnar J, Robert S, Veloso J, Trepotec Z, Englisch S, Weinzierl P, Schick C,
Milani V, Schweneker K, Fleischmann B, Scheiber J, Gandorfer B, Kleespies A, Hempel
D, Riedmann K, Piehler A. Rare SARS-CoV-2 antibody development in cancer patients.
Semin Oncol. 2021 Apr;48(2):160-165. doi: 10.1053/j.seminoncol.2020.12.003. Epub
2021 Jan 2. PMID: 33500147; PMCID: PMC7833493.