75. | Zaradzki M, Rehberg F, Zwaans V, Hecker M, Karck M, Arif R, Soethoff JP, Wagner AH. Stabilisation of extracellular matrix is crucial to rapamycin-mediated life span increase in Marfan mgR/mgR mice. Biochem Pharmacol. 2025 Feb 26;235:116830. doi: 10.1016/j.bcp.2025.116830. Online ahead of print. |
74. | Kunze R, Wacker P, Breuer P, Nasyrov E, Kur IM, Weigert A, Wagner AH, Marti HH, Korff T. Adequate post-ischemic reperfusion of the mouse brain requires endothelial NFAT5. Acta Neuropathol Commun. 2024 Dec 22;12(1):200. doi: 10.1186/s40478-024-01918-5. |
73. | Goo YH, Plakkal Ayyappan J, Cheeran FD, Bangru S, Saha PK, Baar P, Schulz S, Lydic TA, Spengler B, Wagner AH, Kalsotra A, Yechoor VK, Paul A. Lipid droplet-associated hydrolase mobilizes stores of liver X receptor sterol ligands and protects against atherosclerosis. Nat Commun. 2024 Aug 2;15(1):6540. doi: 10.1038/s41467-024-50949-y. |
72. | Noormalal M, Schmiedel N, Bozoglu T, Matzen A, Hille S, Basha, DI, Shetty PMV, Wolf A, Zaradzki M, Arif R, Pühler T, Lutter G, Wagner AH, Kupatt C, Frank D, Frey N, Remes A, Müller OJ. Regnase-1 overexpression as a therapeutic approach of Marfan syndrome. Molecular Therapy: Methods & Clinical Development 2023 Nov 16. doi.org/10.1016/j.omtm.2023.101163. Online ahead of print. |
71. | Joshi P, Mohr F, Rumig C, Kliemank E, Krennig G, Kopf S, Hecker M, Wagner AH. Impact of the -1T>C single-nucleotide polymorphism of the CD40 gene on the development of endothelial dysfunction in a pro-diabetic microenvironment. Atherosclerosis 2023 Nov 14. doi.org/10.1016/j.atherosclerosis.2023.117386. Online ahead of print. |
70. | Klersy A, Meyer S, Leuschner F, Kessler T, Hecker M, Wagner AH. Ectodomain Shedding by ADAM17 Inreases the Release of Soluble CD40 from Human Endothelial Cells under Pro-Inflammatory Conditions. Cells 2023, 12(15), 1926. doi.org/10.3390/cells12151926 |
69. | Lont S, Mohr F, Hecker M, Wagner AH. Role of CD40 ligand-mediated endothelial cell-monocyte interaction at atherosclerosis predilection sites. Biochem Pharmacol. 2022 Oct 12; 206:115298. doi.org/10.1016/j.bcp.2022.115298. Online ahead of print. |
68. | Zaradzki, M, Mohr, F, Lont, S, Soethoff, J, Remes, A, Arif, R, Müller, OJ, Karck, M, Hecker, M, Wagner AH. Short-term rapamycin treatment increases life span and attenuates aortic aneurysm in a murine model of Marfan-Syndrome. Biochem Pharmacol. 2022 Oct 2:115280. doi: 10.1016/j.bcp.2022.115280. Online ahead of print. PMID: 36198355 |
67. | Mathies M, Krieg EM, Mohr F, Zaradzki M, Wagner AH. Effects of Rapamycin on the Expression of Redox Enzymes in Aortic Vascular Smooth Muscle Cells from Marfan Syndrome Mice. Pharmacology 2022 Sep 29: 1-8. doi: 10.1159/000526624. |
66. | Popa M, Hecker M, Wagner AH. Inverse Regulation of Confluence-Dependent ADAMTS13 and von Willebrand Factor Expression in Human Endothelial Cells. Thromb Haemost. 2022 Apr;122(4):611-622. doi: 10.1055/s-0041-1733800. Epub 2021 Aug 5. |
65. | Khamehgir-Silz P, Gerbig S, Volk N, Schulz S, Spengler B, Hecker M, Wagner AH. Comparative lipid profiling of murine and human atherosclerotic plaques using high-resolution MALDI MSI. Pflugers Arch. 2022 Feb;474(2):231-242. doi: 10.1007/s00424-021-02643-x. Epub 2021 Nov 19. |
64. | Remes A, Arif R, Franz M, Jungmann A, Zaradzki M, Puehler T, Md MBH, Frey N, Karck M, Kallenbach K, Hecker M, Müller OJ, Wagner AH. AAV-mediated AP-1 decoy oligonucleotide expression inhibits aortic elastolysis in a mouse model of marfan syndrome. Cardiovasc Res. 2021 2021 Nov 1;117(12):2459-2473. doi: 10.1093/cvr/cvab012. |
63. | Remes A, Wagner AH, Schmiedel N, Heckmann M, Ruf T, Ding L, Jungmann A, Senger F, Katus HA, Ullrich ND, Frey N, Hecker M, Müller OJ. AAV-mediated expression of NFAT decoy oligonucleotides protects from cardiac hypertrophy and heart failure. Basic Res Cardiol. 2021 Jun 4;116(1):38. doi: 10.1007/s00395-021-00880-w. |
62. | Remes A, Basha DI, Puehler T, Borowski C, Hille S, Kummer L, Wagner AH, Hecker M, Soethoff J, Lutter G, Frank D, Arif R, Frey N, Zaradzki M, Müller OJ. Alginate hydrogel polymers enable efficient delivery of a vascular-targeted AAV vector into aortic tissue. Mol Ther Methods Clin Dev. 2021 Jun 11;21:83-93. doi: 10.1016/j.omtm.2021.02.017. eCollection 2021 Jun 11. |
61. | Wäldchen F, Mohr F, Wagner AH, Heiles S. Multifunctional reactive MALDI matrix enabling high-lateral resolution dual polarity MS imaging and lipid C=C position-resolved MS2 imaging. Anal Chem. 2020 Oct 20;92(20):14130-14138. doi: 10.1021/acs.analchem.0c03150. Epub 2020 Sep 28. |
60. | Kummer L, Zaradzki M, Vijayan V, Arif R, Weigand MA, Immenschuh S, Wagner AH, Larmann J. Vascular Signaling in Allogenic Solid Organ Transplantation - The Role of Endothelial Cells. Front Physiol. 2020 May 8;11:443. doi: 10.3389/fphys.2020.00443. eCollection 2020. Review. |
59. | Sultan CS, Weitnauer M, Turinsky M, Kessler T, Brune M, Gleissner CA, Leuschner F, Wagner AH, Hecker M. Functional association of a CD40 gene single nucleotide polymorphism with the pathogenesis of coronary heart disease. Cardiovasc Res. 2020 May 1;116(6):1214-1225. doi: 10.1093/cvr/cvz206. Epub 2019 Aug 2. |
58. | Remes A, Franz M, Zaradzki M, Borowski C, Frey N, Karck M, Kallenbach K, Müller OJ, Wagner AH, Arif R. AAV-mediated TIMP-1 overexpression in aortic tissue reduces the severity of allograft vasculopathy in mice. J Heart Lung Transplant. 2020 Apr;39(4):389-398. doi: 10.1016/j.healun.2020.01.1338. Epub 2020 Jan 30. |
57. | Tahir S, Wagner AH, Dietzel S, Mannell H, Pircher J, Weckbach LT, Hecker M, Pohl U. Endothelial CD40 Mediates Microvascular von Willebrand Factor-Dependent Platelet Adhesion Inducing Inflammatory Venothrombosis in ADAMTS13 Knockout Mice. Thromb Haemost. 2020 Mar;120(3):466-476. doi: 10.1055/s-0040-1702228. Epub 2020 Mar 5. |
56. | Remes A, Franz M, Mohr F, Weber A, Rapti K, Jungmann A, Karck M, Hecker M, Kallenbach K, Müller OJ, Arif R, Wagner AH. AAV-Mediated Expression of AP-1-Neutralizing RNA Decoy Oligonucleotides Attenuates Transplant Vasculopathy in Mouse Aortic Allografts. Mol Ther Methods Clin Dev. 2019 Dec 13;15:246-256. doi: 10.1016/j.omtm.2019.09.009. eCollection 2019 Dec 13. Epub 2019 Oct 2. |
55. | Jiang F, Mohr F, Ullrich ND, Hecker M, Wagner AH. Endothelial cell modulation of cardiomyocyte gene expression. Exp Cell Res. 2019 Oct 15;383(2):111565. doi: 10.1016/j.yexcr.2019.111565. Epub 2019 Aug 20. |
54. | Arif R, Franz M, Remes A, Zaradzki M, Hecker M, Karck M, Müller OJ, Kallenbach K, Wagner AH. Reduction of Transplant Vasculopathy by Intraoperative Nucleic Acid-based Therapy in a Mouse Aortic Allograft Model. Thorac Cardiovasc Surg. 2019 Sep;67(6):503-512. doi: 10.1055/s-0038-1673633. Epub 2018 Oct 23. |
53. | Urban I, Turinsky M, Gehrmann S, Morgenstern J, Brune M, Milewski MR, Wagner AH, Rumig C, Fleming TH, Leuschner F, Gleissner CA, Hecker M. 15-Deoxy-Δ12,14-Prostaglandin J2 Reinforces the Anti-Inflammatory Capacity of Endothelial Cells with a Genetically Determined Nitric Oxide Deficit. Circ Res. 2019 Jul 19;125(3):282-294. doi: 10.1161/CIRCRESAHA.118.313820. Epub 2019 Jun 19. |
52. | Sachdeva R, Fleming T, Schumacher D, Homberg S, Stilz K, Mohr F, Wagner AH, Tsvilovskyy V, Mathar I, Freichel M. Methylglyoxal evokes acute Ca2+ transients in distinct cell types and increases agonist-evoked Ca2+ entry in endothelial cells via CRAC channels. Cell Calcium. 2019 Mar;78:66-75. doi: 10.1016/j.ceca.2019.01.002. Epub 2019 Jan 9. |