Institute Physiologie und… Neuro- und…

Neuro- and sensory physiology

The department deals with a broad spectrum of neuroscientific issues at the level of neuronal networks. The seven research groups work on the mechanisms of coordinated neuronal activity as well as pathophysiological processes in oxygen deficiency, neurodegenerative and inflammatory diseases. We use a broad spectrum of methods from electrophysiology, imaging and behavioural research as well as modern molecular and structural methods.

Prof Andreas Draguhn

Prof Oliver Kann

Prof Alexander Groh

PD Dr Martin Both

Dr Alexei Egorov

Dr Claus Bruehl

Dr Evangelia Pollali

New publications

Draguhn A, Kurtz A. Are you sometimes lost? Read our new Concept Articles! Pflugers Arch. 2024 May;476(5):703. doi: 10.1007/s00424-024-02963-8.

Brito DVC, Kupke J, Sokolov R, Cambridge S, Both M, Bengtson CP, Rozov A, Oliveira AMM. Biphasic Npas4 expression promotes inhibitory plasticity and suppression of fear memory consolidation in mice. Mol Psychiatry. 2024 Feb 13. doi: 10.1038/s41380-024-02454-3. Online ahead of print.

Koumoundourou A, Rannap M, De Bruyckere E, Nestel S, Reissner C, Egorov AV, Liu P, Missler M, Heimrich B, Draguhn A, Britsch S. Regulation of hippocampal mossy fibre-CA3 synapse function by a Bcl11b/C1ql2/Nrxn3(25b+) pathway. Elife. 2024 Feb 15;12:RP89854. doi: 10.7554/eLife.89854.

Stevens NA, Lankisch K, Draguhn A, Engelhardt M, Both M, Thome C. Increased interhemispheric connectivity of a distinct type of hippocampal pyramidal cells. J Neurosci. 2024 Feb 14;44(7):e0440232023. doi: 10.1523/JNEUROSCI.0440-23.2023.

Semino F, Darche FF, Bruehl C, Koenen M, Skladny H, Katus HA, Frey N, Draguhn A, Schweizer PA T. GPD1L-A306del modifies sodium current in a family carrying the dysfunctional SCN5A-G1661R mutation associated with Brugada syndrome. Pflugers Arch. 2024 Feb;476(2):229-242. doi: 10.1007/s00424-023-02882-0. Epub 2023 Dec 1.

Robinson DG, Ammer C, Polle A, Bauhus J, Aloni R, Annighöfer P, Baskin TI, Blatt MR, Bolte A, Bugmann H, Cohen JD, Davies PJ, Draguhn A, Hartmann H, Hasenauer H, Hepler PK, Kohnle U, Lang F, Löf M, Messier C, Munné-Bosch S, Murphy A, Puettmann KJ, Marchant IQ, Raven PH, Robinson D, Sanders D, Seidel D, Schwechheimer C, Spathelf P, Steer M, Taiz L, Wagner S, Henriksson N, Näsholm T. Mother trees, altruistic fungi, and the perils of plant personification. Trends Plant Sci. 2024 Jan;29(1):20-31. doi: 10.1016/j.tplants.2023.08.010. Epub 2023 Sep 19.

Boccuni I, Bas-Orth C, Bruehl C, Draguhn A, Fairless R. Glutamate transporter contribution to retinal ganglion cell vulnerability in a rat model of multiple sclerosis. Neurobiol Dis. 2023 Oct 15;187:106306. doi: 10.1016/j.nbd.2023.106306. epub 2023 Sep 19.

Blatt MR, Draguhn A, Taiz L, Robinson DG.a challenge to claims for mycorrhizal-transmitted wound signalling. plant Signal Behav. 2023 Dec 31;18(1):2222957. doi: 10.1080/15592324.2023.2222957.

Ohara S, Rannap M, Tsutsui KI, Draguhn A, Egorov AV, Witter MP. Hippocampal-medial entorhinal circuit is differently organized along the dorsoventral axis in rodents. Cell Rep. 2023 Jan 31;42(1):112001. doi: 10.1016/j.celrep.2023.112001. epub 2023 Jan 20.

González J, Cavelli M, Mondino A, Castro-Zaballa S, Brankačk J, Draguhn A, Torterolo P, Tort ABL, Draguhn A. Breathing modulates gamma synchronisation across species. Pflugers Arch. 2023 Jan;475(1):49-63. doi: 10.1007/s00424-022-02753-0. Epub 2022 Oct 3.

Jung F, Yanovsky Y, Brankačk J, Tort ABL, Draguhn A. Respiratory entrainment of units in the mouse parietal cortex depends on vigilance state. Pflugers Arch. 2023 Jan;475(1):65-76. doi: 10.1007/s00424-022-02727-2. Epub 2022 Aug 19.

Draguhn A, Sauer JF. Body and mind: how somatic feedback signals shape brain activity and cognition. Pflugers Arch. 2023 Jan;475(1):1-4. doi: 10.1007/s00424-022-02778-5.

Draguhn A, Both M. Function follows form: how the structure of neurons determines cortical network activity : Comment on: Hodapp A, Kaiser ME, Thome C, Ding L, Rozov A, Klumpp M, Stevens N, Stingl M, Sackmann T, Lehmann N, Draguhn A, Burgalossi A, Engelhardt M, Both M (2022) Dendritic axon origin enables information gating by perisomatic inhibition in pyramidal neurons. Science 377:1448-1552. Pflugers Arch. 2023 Mar;475(3):285-287. doi: 10.1007/s00424-022-02776-7. Epub 2022 Dec 3.

Hammer M, Jung F, Brankačk J, Yanovsky Y, Tort ABL, Draguhn A. Respiration and rapid eye movement (REM) sleep substructure: short versus long episodes. J Sleep Res. 2023 Jun;32(3):e13777. doi: 10.1111/jsr.13777. epub 2022 Nov 18.

Hodapp A, Kaiser ME, Thome C, Ding L, Rozov A, Klumpp M, Stevens N, Stingl M, Sackmann T, Lehmann N, Draguhn A, Burgalossi A, Engelhardt M, Both M. Dendritic axon origin enables information gatin by perisomatic inhibition in pyramidal neurons. Science. 2022 Sep 23;377(6613):1448-1452. doi: 10.1126/science.abj1861. Epub 2022 Sep 22.

Draguhn A. No single place for space: neuronal representation of location beyond the hippocampus : Comment on: Sauer JF, Folschweiller S, Bartos M (2022) Topographically organised representation of space and context in the medial prefrontal cortex. Pflugers Arch. 2022 Jun;474(6):569-571. doi: 10.1007/s00424-022-02699-3. Epub 2022 May 7.

Jung F, Witte V, Yanovsky Y, Klumpp M, Brankačk J, Tort, ABL, Draguhn A. Differential modulation of parietal cortex actoivity by respiration and θ oscillations. J Neurophysiol. 2022 Mar 1;127(3):801-817. doi: 10.1152/jn.00376.2021. Epub 2022 Feb 16.

Draguhn A. The mechanics of the brain. J Integr Neurosci. 2022 Jan 28;21(1):22. doi: 10.31083/j.jin2101022.