Publikationen

_51.

_{Kuk H, Arnold C, Meyer R, Hecker M, Korff T. Magnolol inhibits venous remodeling in mice. Sci Rep. 2017 Dec 19;7(1):17820. doi: 10.1038/s41598-017-17910-0.}

_50.

_{Feldner A, Adam MG, Tetzlaff F, Moll I, Komljenovic D, Sahm F, Bäuerle T, Ishikawa H, Schroten H, Korff T, Hofmann I, Wolburg H, von Deimling A, Fischer A. Loss of Mpdz impairs ependymal cell integrity leading to perinatal-onset hydrocephalus in mice. EMBO Mol Med. 2017 Jul;9(7):890-905. doi: 10.15252/emmm.201606430.}

_49.

_{Demolli S, Doddaballapur A, Devraj K, Stark K, Manavski Y, Eckart A, Zehendner CM, Lucas T, Korff T, Hecker M, Massberg S, Liebner S, Kaluza D, Boon RA, Dimmeler S. Shear stress-regulated miR-27b controls pericyte recruitment by repressing SEMA6A and SEMA6D. Cardiovasc Res. 2017 May 1;113(6):681-691. doi: 10.1093/cvr/cvx032.}

_48.

_{Pfisterer L, Korff T. Spheroid-Based In Vitro Angiogenesis Model. Methods Mol Biol. 2016;1430:167-77. doi: 10.1007/978-1-4939-3628-1_11.}

_47.

_{Eschrich J, Meyer R, Kuk H, Wagner AH, Noppeney T, Debus S, Hecker M, Korff T. Varicose Remodeling of Veins Is Suppressed by 3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Inhibitors. J Am Heart Assoc. 2016 Feb 23;5(2). pii: e002405. doi: 10.1161/JAHA.115.002405.}

_46.

_{Schröder H, Komljenovic D, Hecker M, Korff T. Transdermal drug targeting and functional imaging of tumor blood vessels in the mouse auricle. FASEB J. 2016 Feb;30(2):923-32. doi: 10.1096/fj.15-279240. Epub 2015 Nov 6.}

_45.

_{Heiss M, Hellström M, Kalén M, May T, Weber H, Hecker M, Augustin HG, Korff T. Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro. FASEB J. 2015 Jul;29(7):3076-84. doi: 10.1096/fj.14-267633. Epub 2015 Apr 9.}

_44.

_{Ghosh S, Kollar B, Nahar T, Suresh Babu S, Wojtowicz A, Sticht C, Gretz N, Wagner AH, Korff T, Hecker M. Loss of the Mechanotransducer Zyxin Promotes a Synthetic Phenotype of Vascular Smooth Muscle Cells. J Am Heart Assoc. 2015 Jun 12;4(6). pii: e001712.}

_43.

_{Kunze R, Urrutia A, Hoffmann A, Liu H, Helluy X, Pham M, Reischl S, Korff T, Marti HH. Dimethyl fumarate attenuates cerebral edema formation by protecting the blood-brain barrier integrity. Exp Neurol. 2015 Apr;266:99-111. doi: 10.1016/j.expneurol.2015.02.022. Epub 2015 Feb 25.}

_42.

_{Hödebeck M, Scherer C, Wagner AH, Hecker M, Korff T. TonEBP/NFAT5 regulates ACTBL2 expression in biomechanically activated vascular smooth muscle cells. Front Physiol. 2014 Dec 3;5:467. doi: 10.3389/fphys.2014.00467. eCollection 2014.}

_41.

_{Pfisterer L, Meyer R, Feldner A, Drews O, Hecker M, Korff T. Bortezomib protects from varicose-like venous remodeling. FASEB J. 2014 Aug;28(8):3518-27. doi: 10.1096/fj.14-250464. Epub 2014 Apr 25.}

_40.

_{Liu H, Devraj K, Möller K, Liebner S, Hecker M, Korff T. EphrinB-mediated reverse signalling controls junctional integrity and pro-inflammatory differentiation of endothelial cells. Thromb Haemost. 2014 Jul 3;112(1):151-63. doi: 10.1160/TH13-12-1034. Epub 2014 Feb 13.}

_39.

_{Arnold C, Feldner A, Pfisterer L, Hödebeck M, Troidl K, Genové G, Wieland T, Hecker M, Korff T. RGS5 promotes arterial growth during arteriogenesis. EMBO Mol Med. 2014 Jun 27;6(8):1075-89. doi: 10.15252/emmm.201403864.}

_38.

_{Scherer C, Pfisterer L, Wagner AH, Hödebeck M, Cattaruzza M, Hecker M, Korff T. Arterial wall stress controls NFAT5 activity in vascular smooth muscle cells. J Am Heart Assoc. 2014 Mar 10;3(2):e000626. doi: 10.1161/​JAHA.113.000626.}

_37.

_{Korff T, Pfisterer L, Schorpp-Kistner M. miR-663 and the miRaculous Vascular Smooth Muscle Phenotypic Switch. Circ Res. 2013 Oct 25;113(10):1102-5. doi: 10.1161/CIRCRESAHA.113.302578.}

_36.

_{Schröder HM, Hoffmann S, Hecker M, Korff T, Ludwig T. The tetraspanin network modulates MT1-MMP cell surface trafficking. Int J Biochem Cell Biol. 2013 Jun;45(6):1133-44. doi: 10.1016/j.biocel.2013.02.020. Epub 2013 Mar 14.}

_35.

_{Liebler SS, Feldner A, Adam MG, Korff T, Augustin HG, Fischer A. No Evidence for a Functional Role of Bi-Directional Notch Signaling during Angiogenesis. PLoS One. 2012;7(12):e53074. doi: 10.1371/journal.pone.0053074. Epub 2012 Dec 28.}

_34.

_{Pfisterer L, Feldner A, Hecker, M, Korff T. Hypertension impairs myocardin function - a novel mechanism facilitating arterial remodeling. Cardiovasc Res. 2012 Oct 1;96(1):120-9. Epub 2012 Jul 26.}

_33.

_{Varadi K, Michelfelder S, Korff T, Hecker M, Trepel M, Katus HA, Kleinschmidt JA, Müller OJ. Novel random peptide libraries displayed on AAV serotype 9 for selection of endothelial cell-directed gene transfer vectors. Gene Ther. 2012 Aug;19(8):800-9. Epub 2011 Sep 29.}

_32.

_{Korff T, Ernst E, Nobiling R, Feldner A, Reiss Y, Plate KH, Fiedler U, Augustin HG, Hecker M. Angiopoietin-1 mediates inhibition of hypertension-induced release of angiopoietin-2 from endothelial cells. Cardiovasc Res. 2012 Jun 1;94(3):510-8. Epub 2012 Apr 14.}

_31.

_{Navid F, Kolbe L, Stäb F, Korff T, Neufang G. UV-radiation induces the release of angiopoietin-2 from dermal microvascular endothelial cells. Exp Dermatol. 2012 Feb;21(2):147-53. doi: 10.1111/j.1600-0625.2011.01416.x. Epub 2011 Dec 6.}

_30.

_{Feldner A, Otto H, Rewerk S, Hecker M, Korff T. Experimental hypertension triggers varicosis-like maladaptive venous remodeling through activator protein-1. FASEB J. 2011 Oct;25(10):3613-21. Epub 2011 Jun 17.}

_29.

_{Lohr J, Ratliff T, Huppertz A, Ge Y, Dictus C, Ahmadi R, Grau S, Hiraoka N, Eckstein V, Ecker R, Korff T, von Deimling A, Unterberg A, Beckhove P, Herold-Mende CC. Effector T-cell infiltration positively impacts survival of glioblastoma patients and is impaired by tumor-derived transforming growth factor-betas. Clin Cancer Res. 2011 Jul 1;17(13):4296-308. Epub 2011 Apr 8.}

_28.

_{Brecht K, Weigert A, Hu J, Popp R, Fisslthaler B, Korff T, Fleming I, Geisslinger G, Brüne B. Macrophages programmed by apoptotic cells promote angiogenesis via prostaglandin E2. FASEB J. 2011 Jul;25(7):2408-17. Epub 2011 Mar 30.}

_27.

_{Wang Q, Gorbey S, Pfister F, Höger S, Dorn-Beineke A, Krügel K, Berrone E, Wu L, Korff T, Lin J, Busch S, Reichenbach A, Feng Y, Hammes HP. Long-term Treatment with Suberythropoietic Epo is Vaso- and Neuroprotective in Experimental Diabetic Retinopathy. Cell Physiol Biochem. 2011;27(6):769-82. Epub 2011 Jun 17.}

_26.

_{Braun J, Hoffmann SC, Feldner A, Ludwig T, Henning R, Hecker M, Korff T. Endothelial Cell EphrinB2-Dependent Activation of Monocytes in Arteriosclerosis. Arterioscler Thromb Vasc Biol. 2011 Feb;31(2):297-305. Epub 2010 Dec 2.}

_25.

_{Licht AH, Nübel T, Feldner A, Jurisch-Yaksi N, Marcello M, Demicheva E, Hu JH, Hartenstein B, Augustin HG, Hecker M, Angel P, Korff T, Schorpp-Kistner M. Junb regulates arterial contraction capacity, cellular contractility, and motility via its target Myl9 in mice. J Clin Invest. 2010 Jul 1;120(7):2307-18. doi: 10.1172/JCI41749. Epub 2010 Jun 14.}

_24.

_{Limbourg A, Korff T, Napp LC, Schaper W, Drexler H, Limbourg FP. Evaluation of postnatal arteriogenesis and angiogenesis in a mouse model of hind-limb ischemia. Nat Protoc. 2009;4(12):1737-46. Epub 2009 Nov 5.}

_23.

_{Wagner AH, Kautz O, Fricke K, Zerr-Fouineau M, Demicheva E, Güldenzoph B, Bermejo JL, Korff T, Hecker M. Upregulation of glutathione peroxidase offsets stretch-induced proatherogenic gene expression in human endothelial cells. Arterioscler Thromb Vasc Biol. 2009 Nov;29(11):1894-901. Epub 2009 Sep 3.}

_22.

_{Laib AM, Bartol A, Alajati A, Korff T, Weber H, Augustin HG. Spheroid-based human endothelial cell microvessel formation in vivo. Nat Protoc. 2009;4(8):1202-15. Epub 2009 Jul 30.}

_21.

_{Pfaff D, Héroult M, Riedel M, Reiss Y, Kirmse R, Ludwig T, Korff T, Hecker M, Augustin HG. Involvement of endothelial ephrin-B2 in adhesion and transmigration of EphB-receptor-expressing monocytes. J Cell Sci. 2008 Nov 15;121(Pt 22):3842-50. Epub 2008 Oct 28.}

_20.

_{Demicheva E, Hecker M, Korff T. Stretch-induced activation of the transcription factor activator protein-1 controls monocyte chemoattractant protein-1 expression during arteriogenesis. Circ Res. 2008 Aug 29;103(5):477-84. Epub 2008 Jul 31.}

_19.

_{Korff T, Braun J, Pfaff D, Augustin HG, Hecker M. Role of ephrinB2 expression in endothelial cells during arteriogenesis: impact on smooth muscle cell migration and monocyte recruitment. Blood. 2008 Jul 1;112(1):73-81. Epub 2008 Apr 29.}

_18.

_{Alajati A, Laib AM, Weber H, Boos AM, Bartol A, Ikenberg K, Korff T, Zentgraf H, Obodozie C, Graeser R, Christian S, Finkenzeller G, Stark GB, Héroult M, Augustin HG. Spheroid-based engineering of a human vasculature in mice. Nat Methods. 2008 May;5(5):439-45. Epub 2008 Apr 6.}

_17.

_{Webler AC, Popp R, Korff T, Michaelis UR, Urbich C, Busse R, Fleming I. Cytochrome P450 2C9-induced angiogenesis is dependent on EphB4. Arterioscler Thromb Vasc Biol. 2008 Jun;28(6):1123-9. Epub 2008 Mar 13.}

_16.

_{Wirz W, Antoine M, Tag CG, Gressner AM, Korff T, Hellerbrand C, Kiefer P. Hepatic stellate cells display a functional vascular smooth muscle cell phenotype in a three-dimensional co-culture model with endothelial cells. Differentiation. 2008 Sep;76(7):784-94. Epub 2008 Jan 3.}

_15.

_{Korff T, Aufgebauer K, Hecker M. Cyclic stretch controls the expression of CD40 in endothelial cells by changing their transforming growth factor-beta1 response. Circulation. 2007 Nov 13;116(20):2288-97. Epub 2007 Oct 29.}

_14.

_{Goettsch W, Gryczka C, Korff T, Ernst E, Goettsch C, Seebach J, Schnittler HJ, Augustin HG, Morawietz H. Flow-dependent regulation of angiopoietin-2. J Cell Physiol. 2008 Feb;214(2):491-503.}

_13.

_{Korff T, Dandekar G, Pfaff D, Füller T, Goettsch W, Morawietz H, Schaffner F, Augustin HG. Endothelial ephrinB2 is controlled by microenvironmental determinants and associates context-dependently with CD31. Arterioscler Thromb Vasc Biol. 2006 Mar;26(3):468-74. Epub 2005 Dec 15.}

_12.

_{Antoine M, Wirz W, Tag CG, Mavituna M, Emans N, Korff T, Stoldt V, Gressner AM, Kiefer P. Expression pattern of fibroblast growth factors (FGFs), their receptors and antagonists in primary endothelial cells and vascular smooth muscle cells. Growth Factors. 2005 Jun;23(2):87-95.}

_11.

_{Mayer H, Bertram H, Lindenmaier W, Korff T, Weber H, Weich H. Vascular endothelial growth factor (VEGF-A) expression in human mesenchymal stem cells: autocrine and paracrine role on osteoblastic and endothelial differentiation. J Cell Biochem. 2005 Jul 1;95(4):827-39.}

_10.

_{Korff T, Krauss T, Augustin HG. Three-dimensional spheroidal culture of cytotrophoblast cells mimics the phenotype and differentiation of cytotrophoblasts from normal and preeclamptic pregnancies. Exp Cell Res. 2004 Jul 15;297(2):415-23.}

_9.

_{Martiny-Baron G, Korff T, Schaffner F, Esser N, Eggstein S, Marmé D, Augustin HG. Inhibition of tumor growth and angiogenesis by soluble EphB4. Neoplasia. 2004 May-Jun;6(3):248-57.}

_8.

_{Liang OD, Korff T, Eckhardt J, Rifaat J, Baal N, Herr F, Preissner KT, Zygmunt M. Oncodevelopmental alpha-fetoprotein acts as a selective proangiogenic factor on endothelial cell from the fetomaternal unit. J Clin Endocrinol Metab. 2004 Mar;89(3):1415-22.}

_7.

_{Veikkola T, Lohela M, Ikenberg K, Mäkinen T, Korff T, Saaristo A, Petrova T, Jeltsch M, Augustin HG, Alitalo K. Intrinsic versus microenvironmental regulation of lymphatic endothelial cell phenotype and function. FASEB J. 2003 Nov;17(14):2006-13.}

_6.

_{Piossek C, Thierauch KH, Schneider-Mergener J, Volkmer-Engert R, Bachmann MF, Korff T, Augustin HG, Germeroth L. Potent inhibition of angiogenesis by D,L-peptides derived from vascular endothelial growth factor receptor 2. Thromb Haemost. 2003 Sep;90(3):501-10.}

_5.

_{Füller T, Korff T, Kilian A, Dandekar G, Augustin HG. Forward EphB4 signaling in endothelial cells controls cellular repulsion and segregation from ephrinB2 positive cells. J Cell Sci. 2003 Jun 15;116(Pt 12):2461-70. Epub 2003 May 6.}

_4.

_{van Royen N, Hoefer I, Buschmann I, Heil M, Kostin S, Deindl E, Vogel S, Korff T, Augustin H, Bode C, Piek JJ, Schaper W. Exogenous application of transforming growth factor beta 1 stimulates arteriogenesis in the peripheral circulation. FASEB J. 2002 Mar;16(3):432-4. Epub 2002 Jan 30.}

_3.

_{Korff T, Kimmina S, Martiny-Baron G, Augustin HG. Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. FASEB J. 2001 Feb;15(2):447-57.}

_2.

_{Korff T, Augustin HG. Tensional forces in fibrillar extracellular matrices control directional capillary sprouting. J Cell Sci. 1999 Oct;112 ( Pt 19):3249-58.}

_1.

_{Korff T, Augustin HG. Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. J Cell Biol. 1998 Nov 30;143(5):1341-52.}

_6.

_{Kuk H, Jeanneret C, Noppeney T, Korff T. The Biomechanics of Venous Remodeling. In: Vascular Mechanobiology in Physiology and Disease. Cardiac and Vascular Biology, vol 8. (Hecker M, Duncker DJ, eds.) Springer, Cham 2021, pp. 167-189. Hardcover ISBN 978-3-030-63163-5; eBook ISBN: 978-3-030-63164-2}

_5.

_{Pfisterer L, König G, Hecker M, Korff T. Pathogenesis of varicose veins - lessons from biomechanics. Vasa. 2014 March;43(2):88-99.doi: 10.1024/0301-1526/a000335.}

_4.

_{Rewerk S, Meyer R, Hecker M, Korff T. Durch die Augen von Laplace: Die Rolle der Wandspannung bei Varikosis. Phlebologie 2012;41(2):61-7}

_3.

_{Korff T: Kapitel: „Three dimensional in vitro angiogenesis assays“; Methods in Endothelial Cell Biology (Augustin Ed.), Springer Verlag Heidelberg, ISBN 3-540-21397-X, 2004, pp. 115-124}

_2.

_{Korff T: Kapitel: „Three dimensional spheroids culture of endothelial cells“; Methods in Endothelial Cell Biology (Augustin Ed.), Springer Verlag, Heidelberg, ISBN 3-540-21397-X, 2004, pp. 55-62}

_1.

_{Korff T: Kapitel: „Alkohol-Wirkung“; Kaffee, Käse, Karies – Biochemie im Alltag (Koolman, Moeller, Röhm, Hrg.), Wiley-VCH Verlag GmbH, ISBN 3-527-29530-5, 1998, pp. 52-70}