Institute Physiologie und… Herz- und… Thomas Korff Forschung Vascular Organoids for…


Vascular Organoids for Aminal Welfare (3R)

Kappert L, Ruzicka P, Kutikhin A, De La Torre C, Fischer A, Hecker M, Arnold C, Korff T. Loss of Nfat5 promotes lipid accumulation in vascular smooth muscle cells. FASEB J. 2021 Sep;35(9):e21831. doi: 10.1096/fj.202100682R.

Demirel E, Arnold C, Garg J, Jäger MA, Sticht C, Li R, Kuk H, Wettschureck N, Hecker M, Korff T. RGS5 Attenuates Baseline Activity of ERK1/2 and Promotes Growth Arrest of Vascular Smooth Muscle Cells. Cells. 2021 Jul 11;10(7):1748. doi: 10.3390/cells10071748.

Kohlhaas J, Jäger M, Lust L, De La Torre C, Hecker M, Korff T. Endothelial cells control vascular smooth muscle cell cholesterol levels by regulating 24-dehydrocholesterol reductase expression. Exp Cell Res. 2021 Feb 15;399(2):112446. doi: 10.1016/j.yexcr.2020.112446. Epub 2021 Jan 7.

Jäger M, De La Torre C, Arnold C, Kohlhaas J, Kappert L, Hecker M, Feldner A, Korff T. Assembly of vascular smooth muscle cells in 3D aggregates provokes cellular quiescence. Exp Cell Res. 2020 Mar 1;388(1):111782. doi: 10.1016/j.yexcr.2019.111782. Epub 2019 Dec 16.

Pfisterer L, Korff T. Spheroid-Based In Vitro Angiogenesis Model. Methods Mol Biol. 2016;1430:167-77. doi: 10.1007/978-1-4939-3628-1_11.

Heiss M, Hellström M, Kalén M, May T, Weber H, Hecker M, Augustin HG, Korff T. Endothelial cell spheroids as a versatile tool to study angiogenesis in vitro. FASEB J. 2015 Jul;29(7):3076-84. doi: 10.1096/fj.14-267633. Epub 2015 Apr 9.

Korff T, Kimmina S, Martiny-Baron G, Augustin HG. Blood vessel maturation in a 3-dimensional spheroidal coculture model: direct contact with smooth muscle cells regulates endothelial cell quiescence and abrogates VEGF responsiveness. FASEB J. 2001 Feb;15(2):447-57.

Korff T, Augustin HG. Tensional forces in fibrillar extracellular matrices control directional capillary sprouting. J Cell Sci. 1999 Oct;112 ( Pt 19):3249-58.

Korff T, Augustin HG. Integration of endothelial cells in multicellular spheroids prevents apoptosis and induces differentiation. J Cell Biol. 1998 Nov 30;143(5):1341-52.